Literature DB >> 16700282

Does adherence monitoring reduce controlled substance abuse in chronic pain patients?

Laxmaiah Manchikanti1, Rajeev Manchukonda, Kim S Damron, Doris Brandon, Carla D McManus, Kim Cash.   

Abstract

BACKGROUND: Opioids are used extensively for chronic pain management in the United States. The frequency of opioid use prior to presenting to interventional pain management settings and in interventional pain management settings has been shown to be above 90%. Given that controlled substance abuse and illicit drug use are prevalent phenomena, adherence monitoring of patients that are prescribed opioids is becoming common. Adherence monitoring is carried out by an appropriate history, periodic evaluation of appropriate intake of drugs, random drug testing, and pill counts. Crucial to adherence monitoring is an initial controlled substance agreement and repeated review of the terms of this agreement with on-going education. However, the effect of adherence monitoring on drug abuse is unclear.
OBJECTIVE: To identify controlled substance abuse through implementation of the terms of a controlled substance agreement, including periodic review and monitoring outside the organization. STUDY
DESIGN: Prospective evaluation with historical controls.
METHODS: Five hundred consecutive patients receiving prescription controlled substances were followed in a prospective manner. The evaluation consisted of a chart review to monitor controlled substance intake, with special attention to drugs obtained from outside the organization. Data collection for this purpose included information from records, pharmacies, referring physicians, and all the physicians involved in the treatment of the patient.
RESULTS: Results from 500 consecutive patients were evaluated. Controlled substance abuse was seen in 9% of patients; overall, 5% of patients were obtaining controlled substances from other physicians, and 4% from illegal sources.
CONCLUSION: Adherence monitoring, including controlled substance agreements and various periodic measures of compliance was associated with a 50% reduction in opioid abuse.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16700282

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  24 in total

1.  Trends in laboratory test volumes for Medicare Part B reimbursements, 2000-2010.

Authors:  Shahram Shahangian; Todd D Alspach; J Rex Astles; Ajay Yesupriya; William K Dettwyler
Journal:  Arch Pathol Lab Med       Date:  2013-06-05       Impact factor: 5.534

Review 2.  Review of the Current State of Urine Drug Testing in Chronic Pain: Still Effective as a Clinical Tool and Curbing Abuse, or an Arcane Test?

Authors:  Krishnan Chakravarthy; Aneesh Goel; George M Jeha; Alan David Kaye; Paul J Christo
Journal:  Curr Pain Headache Rep       Date:  2021-02-17

Review 3.  [Chronic non-cancer-related pain. Long-term treatment with rapid-release and short-acting opioids in the context of misuse and dependency].

Authors:  R Scharnagel; U Kaiser; A Schütze; R Heineck; G Gossrau; R Sabatowski
Journal:  Schmerz       Date:  2013-02       Impact factor: 1.107

4.  Factors related to compliance with oral analgesic treatment of inpatients with chronic pain.

Authors:  Hong Zhu; Yuzhu Zheng; Hui Gao; Li Liu; Lie Yang
Journal:  Front Med       Date:  2015-08-19       Impact factor: 4.592

Review 5.  Current State of Opioid Therapy and Abuse.

Authors:  Laxmaiah Manchikanti; Adam M Kaye; Alan D Kaye
Journal:  Curr Pain Headache Rep       Date:  2016-05

6.  Trends in Urine Drug Monitoring Among Persons Receiving Long-Term Opioids and Persons with Opioid Use Disorder in the United States.

Authors:  Minji Sohn; Jeffery C Talbert; Zhengyan Huang; Carrie Oser; Patricia R Freeman
Journal:  Pain Physician       Date:  2021-03       Impact factor: 4.965

7.  It made my life a little easier: primary care providers' beliefs and attitudes about using opioid treatment agreements.

Authors:  Joanna L Starrels; Bryan Wu; Deena Peyser; Aaron D Fox; Abigail Batchelder; Frances K Barg; Julia H Arnsten; Chinazo O Cunningham
Journal:  J Opioid Manag       Date:  2014 Mar-Apr

Review 8.  Recommendations for Substance Abuse and Pain Control in Patients with Chronic Pain.

Authors:  Nalini Vadivelu; Alice M Kai; Gopal Kodumudi; Dan Haddad; Vijay Kodumudi; Niketh Kuruvilla; Alan David Kaye; Richard D Urman
Journal:  Curr Pain Headache Rep       Date:  2018-03-19

9.  Denial of prescription opioids among young adults with histories of opioid misuse.

Authors:  Meghan Fibbi; Karol Silva; Kristen Johnson; Debra Langer; Stephen E Lankenau
Journal:  Pain Med       Date:  2012-08-08       Impact factor: 3.750

Review 10.  Buprenorphine Prescribing: To Expand or Not to Expand.

Authors:  Xiaofan Li; Daryl Shorter; Thomas R Kosten
Journal:  J Psychiatr Pract       Date:  2016-05       Impact factor: 1.325

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