PURPOSE: To determine whether there is a difference in surgically induced astigmatism (SIA) and postoperative uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA) between 2 types of clear corneal incisions used in phacoemulsification: the temporal and the on-axis (ie, on the steeper corneal meridian) clear corneal incision (CCTI and CCOI, respectively). SETTING: Moorfields Eye Hospital, London, United Kingdom. METHODS: In a prospective randomized controlled trial (pilot study), 61 eyes with cataract and mild to moderate corneal astigmatism (<2.58 diopters [D] on corneal topography) having phacoemulsification (single surgeon, 3.2 mm incision) were randomized to receive CCTI or CCOI. Main outcome measures included postoperative BCVA and corneal astigmatism and SIA (calculated using the Holladay vector analysis formula). Measurements were repeated postoperatively at 3 weeks in all eyes, whereas only 46 eyes made it to the final assessment at 8 weeks. Continuous variables between groups were compared by Student t test. The power of the study was calculated. RESULTS: At the first follow-up, the difference in SIA between the 2 incision types was 0.15 D and it was not statistically significant (0.65 D in CCOI; 0.50 D in CCTI). At the second follow-up, the difference was 0.29 D and it was statistically significant (0.63 D in CCOI; 0.34 D in CCTI; P = .0004). There was no statistically significant difference in the final postoperative visual acuity. The power of the pilot study was 72%. CONCLUSION: Seven weeks after small-incision phacoemulsification, the CCTI induced less SIA than the CCOI; however, there were no significant differences in the final UCVA and BCVA.
RCT Entities:
PURPOSE: To determine whether there is a difference in surgically induced astigmatism (SIA) and postoperative uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA) between 2 types of clear corneal incisions used in phacoemulsification: the temporal and the on-axis (ie, on the steeper corneal meridian) clear corneal incision (CCTI and CCOI, respectively). SETTING: Moorfields Eye Hospital, London, United Kingdom. METHODS: In a prospective randomized controlled trial (pilot study), 61 eyes with cataract and mild to moderate corneal astigmatism (<2.58 diopters [D] on corneal topography) having phacoemulsification (single surgeon, 3.2 mm incision) were randomized to receive CCTI or CCOI. Main outcome measures included postoperative BCVA and corneal astigmatism and SIA (calculated using the Holladay vector analysis formula). Measurements were repeated postoperatively at 3 weeks in all eyes, whereas only 46 eyes made it to the final assessment at 8 weeks. Continuous variables between groups were compared by Student t test. The power of the study was calculated. RESULTS: At the first follow-up, the difference in SIA between the 2 incision types was 0.15 D and it was not statistically significant (0.65 D in CCOI; 0.50 D in CCTI). At the second follow-up, the difference was 0.29 D and it was statistically significant (0.63 D in CCOI; 0.34 D in CCTI; P = .0004). There was no statistically significant difference in the final postoperative visual acuity. The power of the pilot study was 72%. CONCLUSION: Seven weeks after small-incision phacoemulsification, the CCTI induced less SIA than the CCOI; however, there were no significant differences in the final UCVA and BCVA.
Authors: Jean-Luc Febbraro; Li Wang; Edmondo Borasio; Lorenzo Richiardi; Hamza N Khan; Alain Saad; Damien Gatinel; Douglas D Koch Journal: Graefes Arch Clin Exp Ophthalmol Date: 2014-11-16 Impact factor: 3.117
Authors: Florian Beer; Andreas Wartak; Richard Haindl; Martin Gröschl; Bernhard Baumann; Michael Pircher; Christoph K Hitzenberger Journal: Biomed Opt Express Date: 2017-05-08 Impact factor: 3.732