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Literature DB >> 166922

Inhibition of Herpesvirus hominis replication by human interferon.

Abstract

The effect of human interferon on single-cycle replication of Herpesvirus hominis type 1 (HV-1) and vesicular stomatitis virus (VSV) in human foreskin fibroblast cultures (HFF) was studied. After treatment of HFF cultures with low concentrations (58 U) of human interferon, a variable but statistically significant inhibition of HV-1 was observed. At higher concentrations (greater than 95 U) yield reduction of HV in interferon-treated cultures approached that of VSV. Preliminary data indicate that antiviral activity decays more rapidly for HV-1 than for VSV after removal of interferon from cultures.

Entities: Disease Species

Mesh：

Substances：
Interferons

Year: 1975 PMID： 166922 PMCID： PMC415252 DOI： 10.1128/iai.12.1.104-108.1975

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

9 in total

1. Further studies on an inhibitor of viral activity appearing in infected cell cultures and its role in chronic viral infections.

Authors: M HO; J F ENDERS
Journal: Virology Date: 1959-11 Impact factor: 3.616

2. Interferon and cytomegalovirus in vivo and in vitro.

Authors: L A Glasgow; J B Hanshaw; T C Merigan; J K Petralli
Journal: Proc Soc Exp Biol Med Date: 1967-07

3. Administration of human leukocyte interferon in herpes zoster. I. Safety, circulating, antiviral activity, and host responses to infection.

Authors: G W Jordan; R P Fried; T C Merigan
Journal: J Infect Dis Date: 1974-07 Impact factor: 5.226

4. Sensitivity of ribonucleic acid and deoxyribonucleic acid viruses to different species of interferon in cell cultures.

Authors: J S Youngner; H R Thacore; M E Kelly
Journal: J Virol Date: 1972-08 Impact factor: 5.103

5. Sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex and vaccinia viruses. Induction of resistance by an interferon inducer.

Authors: M Weissenbacher; E Chowchuvech; G Schmunis; L Sawicki; M A Galin
Journal: Proc Soc Exp Biol Med Date: 1973-03

6. [Protection by interferon of human embryo cells against infection by cytomegalic virus].

Authors: M T Thomas; I Gresser
Journal: C R Acad Hebd Seances Acad Sci D Date: 1969-06-23

7. Interference mediated by a variant of Sindbis virus. I. Isolation of an avirulent variant and in vivo interference.

Authors: L E Rasmussen; J A Armstrong; M Ho
Journal: J Infect Dis Date: 1973-08 Impact factor: 5.226

8. Concerning the mechanism of action of interferon.

Authors: W K Joklik; T C Merigan
Journal: Proc Natl Acad Sci U S A Date: 1966-08 Impact factor: 11.205

9. Factors affecting the sensitivity of different viruses to interferon.

Authors: J V Hallum; H R Thacore; J S Youngner
Journal: J Virol Date: 1970-08 Impact factor: 5.103

9 in total

13 in total

9. Effect of cyclic AMP and cyclic GMP on the activity of interferon against herpes simplex virus types 1 and 2, and vesicular stomatitis virus.

Authors: T L Stanwick; A J Nahmias
Journal: Arch Virol Date: 1982 Impact factor: 2.574

10. Interferon susceptibility of herpes simplex virus strains isolated from patients enrolled in clinical trials.

Authors: J A Armstrong; M B Skicki-Mullen; M K Breinig; M Ho
Journal: Antimicrob Agents Chemother Date: 1983-07 Impact factor: 5.191

Inhibition of Herpesvirus hominis replication by human interferon.

1. Further studies on an inhibitor of viral activity appearing in infected cell cultures and its role in chronic viral infections.

2. Interferon and cytomegalovirus in vivo and in vitro.

3. Administration of human leukocyte interferon in herpes zoster. I. Safety, circulating, antiviral activity, and host responses to infection.

4. Sensitivity of ribonucleic acid and deoxyribonucleic acid viruses to different species of interferon in cell cultures.

5. Sensitivity of human conjunctival tissue cultures to adenovirus 8, herpes simplex and vaccinia viruses. Induction of resistance by an interferon inducer.

6. [Protection by interferon of human embryo cells against infection by cytomegalic virus].

7. Interference mediated by a variant of Sindbis virus. I. Isolation of an avirulent variant and in vivo interference.

8. Concerning the mechanism of action of interferon.

9. Factors affecting the sensitivity of different viruses to interferon.

1. Susceptibility of human lymphocyte populations to infection by herpes simplex virus.

2. Effect of recombinant mouse interferon-beta on acute and latent herpes simplex infection in mice.

3. Sensitivity in vitro of herpes simplex virus isolates to human fibroblast interferon.

4. Combined antiviral effect of interferon and acyclovir on herpes simplex virus types 1 and 2.

5. Inhibition of human herpesviruses by combination of acyclovir and human leukocyte interferon.

6. Susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection.

7. Response of cloned progeny of clinical isolates of herpes simplex virus to human leukocyte interferon.

8. Effect of acyclovir on the proliferation of human fibroblasts and peripheral blood mononuclear cells.

9. Effect of cyclic AMP and cyclic GMP on the activity of interferon against herpes simplex virus types 1 and 2, and vesicular stomatitis virus.

10. Interferon susceptibility of herpes simplex virus strains isolated from patients enrolled in clinical trials.