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Literature DB >> 16687246

Actin in transcription and transcription regulation.

Abstract

Recent research has provided convincing evidence that actin plays several important roles in gene transcription. First, actin can bind transcription factors and determine their subcellular localization. Second, actin is a component of chromatin remodeling complexes involved in transcriptional activation. Third, actin binds directly to the RNA polymerases I, II and III, and is required for their full transcriptional activity. Fourth, actin associates with nascent mRNPs and participates in the recruitment of histone modifiers to transcribed genes. We do not know yet whether these functions are general, or restricted to certain subsets of genes.

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Year: 2006 PMID： 16687246 DOI： 10.1016/j.ceb.2006.04.009

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

66 in total

1. A fluorophore ligase for site-specific protein labeling inside living cells.

Authors: Chayasith Uttamapinant; Katharine A White; Hemanta Baruah; Samuel Thompson; Marta Fernández-Suárez; Sujiet Puthenveetil; Alice Y Ting
Journal: Proc Natl Acad Sci U S A Date: 2010-06-07 Impact factor: 11.205

2. The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells.

Authors: Simran Khurana; Sharmistha Chakraborty; Xiwen Cheng; Yu-Ting Su; Hung-Ying Kao
Journal: J Biol Chem Date: 2010-11-15 Impact factor: 5.157

3. An active mechanism flanks and modulates the export of the small ribosomal subunits.

Authors: Barbara Cisterna; Manuela Malatesta; Jürgen Dieker; Sylviane Muller; Ennio Prosperi; Marco Biggiogera
Journal: Histochem Cell Biol Date: 2009-03-18 Impact factor: 4.304

Review 4. Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?

Authors: P Bryant Chase; Mark P Szczypinski; Elliott P Soto
Journal: J Muscle Res Cell Motil Date: 2013-08-02 Impact factor: 2.698

5. Probing the dynamic organization of transcription compartments and gene loci within the nucleus of living cells.

Authors: Deepak Kumar Sinha; Bidisha Banerjee; Shovamayee Maharana; G V Shivashankar
Journal: Biophys J Date: 2008-09-19 Impact factor: 4.033

6. Mutational analysis reveals a noncontractile but interactive role of actin and profilin in viral RNA-dependent RNA synthesis.

Authors: Mary Harpen; Tiasha Barik; Alla Musiyenko; Sailen Barik
Journal: J Virol Date: 2009-08-26 Impact factor: 5.103

Actin in transcription and transcription regulation.

1. A fluorophore ligase for site-specific protein labeling inside living cells.

2. The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells.

3. An active mechanism flanks and modulates the export of the small ribosomal subunits.

Review 4. Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?

5. Probing the dynamic organization of transcription compartments and gene loci within the nucleus of living cells.

6. Mutational analysis reveals a noncontractile but interactive role of actin and profilin in viral RNA-dependent RNA synthesis.

7. A transcription co-factor integrates cell adhesion and motility with the p53 response.

Review 8. Structure and epigenetics of nucleoli in comparison with non-nucleolar compartments.

9. Flavonoids affect actin functions in cytoplasm and nucleus.

10. Effect of destrin mutations on the gene expression profile in vivo.