Literature DB >> 16678795

Modification of Msx1 by SUMO-1.

Vandana Gupta1, Marianna Bei.   

Abstract

The small ubiquitin-related modifier SUMO reversibly modifies many proteins, including promoter-specific transcription factors. Genetic studies in both humans and mice indicate that the Msx1 transcription factor is associated with specific disorders, including cleft palate. We show that Msx1 conjugation to SUMO-1 in vivo is enhanced by an E3 SUMO ligase, PIAS1, suggesting that sumoylation of Msx1 is a new mechanism for modulating the molecular function of Msx1 during organogenesis.

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Year:  2006        PMID： 16678795     DOI： 10.1016/j.bbrc.2006.03.232

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

Review 1.  What is bad in cancer is good in the embryo: importance of EMT in neural crest development.

Authors:  Laura Kerosuo; Marianne Bronner-Fraser
Journal:  Semin Cell Dev Biol       Date:  2012-03-10       Impact factor: 7.727

2.  Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription.

Authors:  Ken'ichiro Hayashi; Seiji Nakamura; Wataru Nishida; Kenji Sobue
Journal:  Mol Cell Biol       Date:  2006-10-09       Impact factor: 4.272

3.  Genotype phenotype correlation of 30 patients with Smith-Magenis syndrome (SMS) using comparative genome hybridisation array: cleft palate in SMS is associated with larger deletions.

Authors:  J Andrieux; C Villenet; S Quief; S Lignon; S Geffroy; C Roumier; H de Leersnyder; M-C de Blois; S Manouvrier; B Delobel; B Benzacken; P Bitoun; T Attie-Bitach; S Thomas; S Lyonnet; M Vekemans; J-P Kerckaert
Journal:  J Med Genet       Date:  2007-04-27       Impact factor: 6.318

4.  The spindle positioning protein Kar9p interacts with the sumoylation machinery in Saccharomyces cerevisiae.

Authors:  Nida Meednu; Harold Hoops; Sonia D'Silva; Leah Pogorzala; Schuyler Wood; David Farkas; Mark Sorrentino; Elaine Sia; Pam Meluh; Rita K Miller
Journal:  Genetics       Date:  2008-10-01       Impact factor: 4.562

5.  A network of transcription factors operates during early tooth morphogenesis.

Authors:  Minglian Zhao; Vandana Gupta; Lakshmi Raj; Martine Roussel; Marianna Bei
Journal:  Mol Cell Biol       Date:  2013-06-10       Impact factor: 4.272

6.  Sumoylation of the basic helix-loop-helix transcription factor sharp-1 regulates recruitment of the histone methyltransferase G9a and function in myogenesis.

Authors:  Yaju Wang; Shilpa Rani Shankar; Devaki Kher; Belinda Mei Tze Ling; Reshma Taneja
Journal:  J Biol Chem       Date:  2013-04-30       Impact factor: 5.157

7.  TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression.

Authors:  Artemisia M Andreou; Erwin Pauws; Marius C Jones; Manvendra K Singh; Markus Bussen; Kit Doudney; Gudrun E Moore; Andreas Kispert; Jan J Brosens; Philip Stanier
Journal:  Am J Hum Genet       Date:  2007-08-16       Impact factor: 11.025

8.  Molecular signaling along the anterior-posterior axis of early palate development.

Authors:  Tara M Smith; Scott Lozanoff; Paul P Iyyanar; Adil J Nazarali
Journal:  Front Physiol       Date:  2013-01-07       Impact factor: 4.566

Review 9.  Assessment of candidate genes and genetic heterogeneity in human non syndromic orofacial clefts specifically non syndromic cleft lip with or without palate.

Authors:  Komal Saleem; Tahir Zaib; Wenjing Sun; Songbin Fu
Journal:  Heliyon       Date:  2019-12-13

10.  Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation.

Authors:  Kamini Kaushal; Apoorvi Tyagi; Janardhan Keshav Karapurkar; Eun-Jung Kim; Parthasaradhireddy Tanguturi; Kye-Seong Kim; Han-Sung Jung; Suresh Ramakrishna
Journal:  Int J Mol Sci       Date:  2022-01-13       Impact factor: 5.923
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