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Literature DB >> 16677801

Biosynthesis and trafficking of seven transmembrane receptor signalling complexes.

Abstract

Recent studies have shown that 7-transmembrane receptors (7TM-Rs), their associated signalling molecules and scaffolding proteins are often constitutively associated under basal conditions. These studies highlight that receptor ontogeny and trafficking are likely to play key roles in the determination of both signalling specificity and efficacy. This review highlights information about how 7TM-Rs and their associated signalling molecules are trafficked to the cell surface as well as other intracellular destinations.

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Year: 2006 PMID： 16677801 DOI： 10.1016/j.cellsig.2006.03.009

Source DB: PubMed Journal: Cell Signal ISSN： 0898-6568 Impact factor: 4.315

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Cited

24 in total

1. Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion.

Authors: Xue-Zhi Li; Jing Yan; Shu-Hong Huang; Ling Zhao; Jue Wang; Zhe-Yu Chen
Journal: J Biol Chem Date: 2011-11-29 Impact factor: 5.157

Review 2. The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels.

Authors: Peter Zylbergold; Nitya Ramakrishnan; Terence Hebert
Journal: Channels (Austin) Date: 2010-09-01 Impact factor: 2.581

3. Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.

Authors: Roshanak Irannejad; Philip B Wedegaertner
Journal: J Biol Chem Date: 2010-08-18 Impact factor: 5.157

Review 4. Regulation of G protein-coupled receptor export trafficking.

Authors: Chunmin Dong; Catalin M Filipeanu; Matthew T Duvernay; Guangyu Wu
Journal: Biochim Biophys Acta Date: 2006-09-23

Review 5. Supramolecular assemblies and localized regulation of voltage-gated ion channels.

Authors: Shuiping Dai; Duane D Hall; Johannes W Hell
Journal: Physiol Rev Date: 2009-04 Impact factor: 37.312

6. Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

Authors: Nicolas Audet; Céline Galés; Elodie Archer-Lahlou; Marc Vallières; Peter W Schiller; Michel Bouvier; Graciela Pineyro
Journal: J Biol Chem Date: 2008-04-01 Impact factor: 5.157

Biosynthesis and trafficking of seven transmembrane receptor signalling complexes.

1. Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion.

Review 2. The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels.

3. Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.

Review 4. Regulation of G protein-coupled receptor export trafficking.

Review 5. Supramolecular assemblies and localized regulation of voltage-gated ion channels.

6. Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins.

Review 7. In search of analgesia: emerging roles of GPCRs in pain.

Review 8. Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling.

9. Postendocytotic traffic of the galanin R1 receptor: a lysosomal signal motif on the cytoplasmic terminus.

10. GABA-B(1) receptors are coupled to the ERK1/2 MAP kinase pathway in the absence of GABA-B(2) subunits.