Literature DB >> 16677672

Experimental radiofrequency ablation near the portal and the hepatic veins in pigs: differences in efficacy of a monopolar ablation system.

Christopher Bangard1, Axel Gossmann, Hans U Kasper, Martin Hellmich, Jürgen H Fischer, Arnulf Hölscher, Klaus Lackner, Dirk L Stippel.   

Abstract

BACKGROUND: We sought to compare the efficacy of a monopolar radiofrequency ablation system in vivo near the portal vein and the hepatic veins in porcine liver.
MATERIALS AND METHODS: Radiofrequency ablation of healthy livers near the portal vein and the hepatic veins was performed in 10 pigs with a multitined expandable electrode. Volumes and diameters of zones of ablation were assessed by magnetic resonance imaging.
RESULTS: Volumes (16.0 +/- 5.5 mL, P = 0.001) and diameters (4.0 +/- 0.7 cm, 3.3 +/- 0.7 cm, 3.0 +/- 0.6 cm, P <or= 0.05) of the zones of ablation near the hepatic veins were larger than that near the portal vein (7.5 +/- 4.1 mL, 3.2 +/- 0.7 cm, 2.6 +/- 0.7 cm, 2.4 +/- 0.6 cm). Energy deposition needed to ablate liver tissue was higher (P = 0.003) for radiofrequency ablation near the portal vein (3.16 +/- 1.58 kJ/mL) than for radiofrequency ablation near the hepatic veins (1.65 +/- 1.14 kJ/mL).
CONCLUSIONS: Higher energy deposition is needed to ablate liver tissue near the portal vein than near the hepatic veins. As a result, the zone of ablation is larger near the hepatic vein than near the portal vein.

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Year:  2006        PMID: 16677672     DOI: 10.1016/j.jss.2006.02.026

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  7 in total

1.  Which parameters are needed for targeting a multitined radiofrequency device--an approach to a simple algorithm.

Authors:  Dirk L Stippel; Christopher Bangard; Klaus Prenzel; Selim Yavuzyasar; Jürgen H Fischer; Arnulf H Hölscher
Journal:  Langenbecks Arch Surg       Date:  2008-02-21       Impact factor: 3.445

2.  Can we ablate liver lesions close to large portal and hepatic veins with MR-guided HIFU? An experimental study in a porcine model.

Authors:  Ulrik Carling; Leonid Barkhatov; Henrik M Reims; Tryggve Storås; Frederic Courivaud; Airazat M Kazaryan; Per Steinar Halvorsen; Eric Dorenberg; Bjørn Edwin; Per Kristian Hol
Journal:  Eur Radiol       Date:  2019-02-08       Impact factor: 5.315

3.  Experimental study of destruction to porcine spleen in vivo by microwave ablation.

Authors:  Fei Gao; Yang-Kui Gu; Jing-Xian Shen; Chang-Lun Li; Xiong-Ying Jiang; Jin-Hua Huang
Journal:  World J Gastroenterol       Date:  2011-12-07       Impact factor: 5.742

4.  Fast Estimation of the Vascular Cooling in RFA Based on Numerical Simulation.

Authors:  T Kröger; T Pätz; I Altrogge; A Schenk; K S Lehmann; B B Frericks; J-P Ritz; H-O Peitgen; T Preusser
Journal:  Open Biomed Eng J       Date:  2010-02-04

5.  Large-volume multi-tined expandable RF ablation in pig livers: comparison of 2D and volumetric measurements of the ablation zone.

Authors:  Christopher Bangard; Silvia Rösgen; Roger Wahba; Rafael Wiemker; Martin Hellmich; Hannah Reiter; Jürgen H Fischer; Dirk L Stippel; Klaus J Lackner
Journal:  Eur Radiol       Date:  2009-11-14       Impact factor: 5.315

6.  Perivascular vital cells in the ablation center after multibipolar radiofrequency ablation in an in vivo porcine model.

Authors:  F G M Poch; C A Neizert; B Geyer; O Gemeinhardt; S M Niehues; J L Vahldiek; K K Bressem; K S Lehmann
Journal:  Sci Rep       Date:  2021-07-06       Impact factor: 4.379

7.  Feasibility of radiofrequency ablation as an alternative to surgical intervention in patients with huge multiloculated pyogenic liver abscesses: A retrospective cohort study.

Authors:  Shan Ke; Xue-Mei Ding; Jun Gao; Shao-Hong Wang; Jian Kong; Li Xu; Wen-Bing Sun
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.817

  7 in total

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