| Literature DB >> 16672432 |
Fanrong Kong1, Mitchell Brown, Archcna Sabananthan, Xianyu Zeng, Gwendolyn L Gilbert.
Abstract
We developed a multiplex PCR-based reverse line blot assay to identify 23 pneumococcal serotypes represented in the polysaccharide vaccine, using 334 well-characterized isolates, representing all 90 serotypes, and 268 "unknowns." The assay identified all target serotypes, but 11, which cross-react with 1 to 4 nonvaccine serotypes, could be distinguished using serotype-specific antisera.Entities:
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Year: 2006 PMID: 16672432 PMCID: PMC1479170 DOI: 10.1128/JCM.44.5.1887-1891.2006
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948