Literature DB >> 16672418

Cytolethal distending toxin in Escherichia coli O157:H7: spectrum of conservation, structure, and endothelial toxicity.

Alexander W Friedrich1, Shan Lu, Martina Bielaszewska, Rita Prager, Phillip Bruns, Jian-Guo Xu, Helmut Tschäpe, Helge Karch.   

Abstract

We identified the cytolethal distending toxin V (CDT-V) gene cluster in 19 (4.9%) of 391 enterohemorrhagic Escherichia coli O157:H7. cdt-V+ strains belonged to five phage types (PTs) and were most frequent within PTs 14 and 34. CDT-V was expressed in all but two cdt-V+ strains and was lethal to cultured endothelial cells. Subtyping schemes should include cdt-V as a marker to differentiate E. coli O157:H7 even within the same phage type.

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Year:  2006        PMID: 16672418      PMCID: PMC1479162          DOI: 10.1128/JCM.44.5.1844-1846.2006

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  20 in total

1.  Epidemiologic subtyping of Escherichia coli serogroup O157 strains isolated in Ontario by phage typing and pulsed-field gel electrophoresis.

Authors:  M A Preston; W Johnson; R Khakhria; A Borczyk
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

2.  Phenotypic and genotypic analyses of enterohemorrhagic Escherichia coli O145 strains from patients in Germany.

Authors:  Anne-Katharina Sonntag; Rita Prager; Martina Bielaszewska; Wenlan Zhang; Angelika Fruth; Helmut Tschäpe; Helge Karch
Journal:  J Clin Microbiol       Date:  2004-03       Impact factor: 5.948

3.  Characterization of cytolethal distending toxin genes and expression in shiga toxin-producing Escherichia coli strains of non-O157 serogroups.

Authors:  Martina Bielaszewska; Marina Fell; Lilo Greune; Rita Prager; Angelika Fruth; Helmut Tschäpe; M Alexander Schmidt; Helge Karch
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

4.  Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms.

Authors:  Alexander W Friedrich; Martina Bielaszewska; Wen-Lan Zhang; Matthias Pulz; Thorsten Kuczius; Andrea Ammon; Helge Karch
Journal:  J Infect Dis       Date:  2001-12-14       Impact factor: 5.226

5.  Presence and characterization of a mosaic genomic island which distinguishes sorbitol-fermenting enterohemorrhagic Escherichia coli O157:H- from E. coli O157:H7.

Authors:  Andreas Janka; Georg Becker; Anne-Katharina Sonntag; Martina Bielaszewska; Ulrich Dobrindt; Helge Karch
Journal:  Appl Environ Microbiol       Date:  2005-08       Impact factor: 4.792

6.  Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.

Authors:  N T Perna; G Plunkett; V Burland; B Mau; J D Glasner; D J Rose; G F Mayhew; P S Evans; J Gregor; H A Kirkpatrick; G Pósfai; J Hackett; S Klink; A Boutin; Y Shao; L Miller; E J Grotbeck; N W Davis; A Lim; E T Dimalanta; K D Potamousis; J Apodaca; T S Anantharaman; J Lin; G Yen; D C Schwartz; R A Welch; F R Blattner
Journal:  Nature       Date:  2001-01-25       Impact factor: 49.962

7.  Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.

Authors:  T Hayashi; K Makino; M Ohnishi; K Kurokawa; K Ishii; K Yokoyama; C G Han; E Ohtsubo; K Nakayama; T Murata; M Tanaka; T Tobe; T Iida; H Takami; T Honda; C Sasakawa; N Ogasawara; T Yasunaga; S Kuhara; T Shiba; M Hattori; H Shinagawa
Journal:  DNA Res       Date:  2001-02-28       Impact factor: 4.458

8.  The Haemophilus ducreyi cytolethal distending toxin induces cell cycle arrest and apoptosis via the DNA damage checkpoint pathways.

Authors:  X Cortes-Bratti; C Karlsson; T Lagergård; M Thelestam; T Frisan
Journal:  J Biol Chem       Date:  2000-11-13       Impact factor: 5.157

9.  Cytolethal distending toxin gene cluster in enterohemorrhagic Escherichia coli O157:H- and O157:H7: characterization and evolutionary considerations.

Authors:  Andreas Janka; Martina Bielaszewska; Ulrich Dobrindt; Lilo Greune; M Alexander Schmidt; Helge Karch
Journal:  Infect Immun       Date:  2003-06       Impact factor: 3.441

10.  Characteristics and association with disease of two major subclones of Shiga toxin (Verocytotoxin)-producing strains of Escherichia coli (STEC) O157 that are present among isolates from patients in Germany.

Authors:  Lothar Beutin; Stefan Kaulfuss; Thomas Cheasty; Börries Brandenburg; Sonja Zimmermann; Kerstin Gleier; Geraldine A Willshaw; Henry R Smith
Journal:  Diagn Microbiol Infect Dis       Date:  2002-12       Impact factor: 2.803

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  23 in total

1.  Bacteriophage-encoding cytolethal distending toxin type V gene induced from nonclinical Escherichia coli isolates.

Authors:  Anna Allué-Guardia; Cristina García-Aljaro; Maite Muniesa
Journal:  Infect Immun       Date:  2011-06-06       Impact factor: 3.441

Review 2.  Facing glycosphingolipid-Shiga toxin interaction: dire straits for endothelial cells of the human vasculature.

Authors:  Andreas Bauwens; Josefine Betz; Iris Meisen; Björn Kemper; Helge Karch; Johannes Müthing
Journal:  Cell Mol Life Sci       Date:  2012-07-06       Impact factor: 9.261

Review 3.  Recent advances in understanding enteric pathogenic Escherichia coli.

Authors:  Matthew A Croxen; Robyn J Law; Roland Scholz; Kristie M Keeney; Marta Wlodarska; B Brett Finlay
Journal:  Clin Microbiol Rev       Date:  2013-10       Impact factor: 26.132

4.  Sequence variability of P2-like prophage genomes carrying the cytolethal distending toxin V operon in Escherichia coli O157.

Authors:  Domonkos Sváb; Balázs Horváth; Gergely Maróti; Ulrich Dobrindt; István Tóth
Journal:  Appl Environ Microbiol       Date:  2013-06-14       Impact factor: 4.792

5.  Shiga toxin, cytolethal distending toxin, and hemolysin repertoires in clinical Escherichia coli O91 isolates.

Authors:  Martina Bielaszewska; Franziska Stoewe; Angelika Fruth; Wenlan Zhang; Rita Prager; Jens Brockmeyer; Alexander Mellmann; Helge Karch; Alexander W Friedrich
Journal:  J Clin Microbiol       Date:  2009-04-29       Impact factor: 5.948

6.  An inducible lambdoid prophage encoding cytolethal distending toxin (Cdt-I) and a type III effector protein in enteropathogenic Escherichia coli.

Authors:  Masahiro Asakura; Atsushi Hinenoya; Mohammad S Alam; Kensuke Shima; Shamim Hasan Zahid; Lei Shi; Norihiko Sugimoto; A N Ghosh; T Ramamurthy; Shah M Faruque; G Balakrish Nair; Shinji Yamasaki
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-28       Impact factor: 11.205

7.  Evolution of a self-inducible cytolethal distending toxin type V-encoding bacteriophage from Escherichia coli O157:H7 to Shigella sonnei.

Authors:  Anna Allué-Guardia; Lejla Imamovic; Maite Muniesa
Journal:  J Virol       Date:  2013-10-09       Impact factor: 5.103

8.  Molecular analysis of virulence profiles and Shiga toxin genes in food-borne Shiga toxin-producing Escherichia coli.

Authors:  T Slanec; A Fruth; K Creuzburg; H Schmidt
Journal:  Appl Environ Microbiol       Date:  2009-08-14       Impact factor: 4.792

9.  Virulence genes and molecular typing of different groups of Escherichia coli O157 strains in cattle.

Authors:  István Tóth; Herbert Schmidt; Gábor Kardos; Zsuzsanna Lancz; Kristina Creuzburg; Ivelina Damjanova; Judit Pászti; Lothar Beutin; Béla Nagy
Journal:  Appl Environ Microbiol       Date:  2009-08-14       Impact factor: 4.792

10.  Anaerobic conditions promote expression of Sfp fimbriae and adherence of sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM to human intestinal epithelial cells.

Authors:  Anne Müsken; Martina Bielaszewska; Lilo Greune; Christian H Schweppe; Johannes Müthing; Herbert Schmidt; M Alexander Schmidt; Helge Karch; Wenlan Zhang
Journal:  Appl Environ Microbiol       Date:  2007-12-14       Impact factor: 4.792

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