| Literature DB >> 16671781 |
Sonia A van der Sar1, John W Blunt, Murray H G Munro.
Abstract
[structure: see text] A spirobisnaphthalene derivative with a new spiro-nonadiene skeleton, spiro-mamakone A (1), has been isolated from the extract of a cultured nonsporulating fungal endophyte derived from the New Zealand native tree Knightia excelsa (rewarewa). The carbon skeleton of spiro-mamakone A represents a new structural entity and an intriguing addition to the structurally diverse spirobisnaphthalene group of compounds. spiro-Mamakone A is potently cytotoxic and is also antimicrobial.Entities:
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Year: 2006 PMID: 16671781 DOI: 10.1021/ol060434k
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005