Literature DB >> 16651491

Error reduction in pediatric chemotherapy: computerized order entry and failure modes and effects analysis.

George R Kim1, Allen R Chen, Robert J Arceci, Sandra H Mitchell, K Michelle Kokoszka, Denise Daniel, Christoph U Lehmann.   

Abstract

OBJECTIVE: To implement and evaluate the impact of computerized provider order entry (CPOE) on reducing ordering errors in pediatric chemotherapy.
DESIGN: Before-and-after study from 2001 to 2004.
SETTING: Pediatric Oncology in an academic medical center. INTERVENTION: Implementation of a CPOE system guided by multidisciplinary failure modes and effects analysis into pediatric chemotherapy. MAIN OUTCOME MEASURES: Completion data on chemotherapy steps of high morbidity/mortality potential if missed (as determined by attending oncologists) from 1259 pre-CPOE paper and 1116 post-CPOE pediatric chemotherapy orders.
RESULTS: After CPOE deployment, daily chemotherapy orders were less likely to have improper dosing (relative risk [RR], 0.26; 95% confidence interval [CI], 0.11-0.61), incorrect dosing calculations (RR, 0.09; 95% CI, 0.03-0.34), missing cumulative dose calculations (RR, 0.32; 95% CI, 0.14-0.77), and incomplete nursing checklists (RR, 0.51; 95% CI, 0.33-0.80). There was no difference in the likelihood of improper dosing on treatment plans and a higher likelihood of not matching medication orders to treatment plans (RR, 5.4; 95% CI, 3.1-9.5).
CONCLUSION: Failure modes and effects analysis-guided CPOE reduced ordering errors in pediatric chemotherapy and provided data for further improvements.

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Year:  2006        PMID: 16651491     DOI: 10.1001/archpedi.160.5.495

Source DB:  PubMed          Journal:  Arch Pediatr Adolesc Med        ISSN: 1072-4710


  31 in total

1.  Computerized provider order entry in pediatric oncology: design, implementation, and outcomes.

Authors:  Allen R Chen; Christoph U Lehmann
Journal:  J Oncol Pract       Date:  2011-07       Impact factor: 3.840

2.  Applying HFMEA to prevent chemotherapy errors.

Authors:  Chia-Hui Cheng; Chia-Jen Chou; Pa-Chun Wang; Hsi-Yen Lin; Chi-Lan Kao; Chao-Ton Su
Journal:  J Med Syst       Date:  2010-11-11       Impact factor: 4.460

3.  Safe Implementation of Computerized Provider Order Entry for Adult Oncology.

Authors:  D B Martin; D Kaemingk; D Frieze; P Hendrie; T H Payne
Journal:  Appl Clin Inform       Date:  2015-10-28       Impact factor: 2.342

4.  Effect of computerisation on the quality and safety of chemotherapy prescription.

Authors:  Marc Voeffray; André Pannatier; Roger Stupp; Nadia Fucina; Serge Leyvraz; Jean-Blaise Wasserfallen
Journal:  Qual Saf Health Care       Date:  2006-12

Review 5.  Does computerized provider order entry reduce prescribing errors for hospital inpatients? A systematic review.

Authors:  Margaret H Reckmann; Johanna I Westbrook; Yvonne Koh; Connie Lo; Richard O Day
Journal:  J Am Med Inform Assoc       Date:  2009-06-30       Impact factor: 4.497

Review 6.  The effect of electronic prescribing on medication errors and adverse drug events: a systematic review.

Authors:  Elske Ammenwerth; Petra Schnell-Inderst; Christof Machan; Uwe Siebert
Journal:  J Am Med Inform Assoc       Date:  2008-06-25       Impact factor: 4.497

7.  Toward successful migration to computerized physician order entry for chemotherapy.

Authors:  J Jeon; S Taneva; V Kukreti; P Trbovich; A C Easty; P G Rossos; J A Cafazzo
Journal:  Curr Oncol       Date:  2014-04       Impact factor: 3.677

8.  Clinical Informatics Fellowship Programs: In Search of a Viable Financial Model: An open letter to the Centers for Medicare and Medicaid Services.

Authors:  C U Lehmann; C A Longhurst; W Hersh; V Mohan; B P Levy; P J Embi; J T Finnell; A M Turner; R Martin; J Williamson; B Munger
Journal:  Appl Clin Inform       Date:  2015-04-15       Impact factor: 2.342

Review 9.  Computerized clinical decision support for medication prescribing and utilization in pediatrics.

Authors:  Jeremy S Stultz; Milap C Nahata
Journal:  J Am Med Inform Assoc       Date:  2012-07-19       Impact factor: 4.497

Review 10.  Application of biomedical informatics to chronic pediatric diseases: a systematic review.

Authors:  Fatemeh Moeinedin; Rahim Moineddin; Alejandro R Jadad; Jemila S Hamid; Teresa To; Joseph Beyene
Journal:  BMC Med Inform Decis Mak       Date:  2009-05-05       Impact factor: 2.796

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