Literature DB >> 16651402

Exploring a new twist on tumor metastasis.

Jing Yang1, Sendurai A Mani, Robert A Weinberg.   

Abstract

Unraveling the genetic programs that drive -metastasis may offer insights into how to limit or prevent this deadly aspect of cancer progression. Our recent studies indicate that tumor cell metastasis involves the activity of the transcription factor, Twist, which regulates epithelial-mesenchymal transition and early embryonic morphogenesis. Here, we review the Twist signaling pathway during normal development and discuss how the transcription factor Twist and the epithelial-mesenchymal transition program impinge their biological functions during tumor metastasis.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16651402     DOI： 10.1158/0008-5472.CAN-05-3850

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  111 in total

1.  Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion.

Authors:  Hezhe Lu; Jianglan Liu; Shujing Liu; Jingwen Zeng; Deqiang Ding; Russ P Carstens; Yusheng Cong; Xiaowei Xu; Wei Guo
Journal:  Dev Cell       Date:  2013-12-09       Impact factor: 12.270

2.  Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development.

Authors:  Elaine L Shelton; Katherine E Yutzey
Journal:  Dev Biol       Date:  2008-02-29       Impact factor: 3.582

Review 3.  Metastamirs: a stepping stone towards improved cancer management.

Authors:  Nicole M A White; Eman Fatoohi; Maged Metias; Klaus Jung; Carsten Stephan; George M Yousef
Journal:  Nat Rev Clin Oncol       Date:  2010-11-02       Impact factor: 66.675

4.  Breast cancer progression: controversies and consensus in the molecular mechanisms of metastasis and EMT.

Authors:  Pamela Cowin; Danny R Welch
Journal:  J Mammary Gland Biol Neoplasia       Date:  2007-09       Impact factor: 2.673

5.  Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma.

Authors:  Sun Mi Hong; Chang Wook Park; Hyung Jin Cha; Jung Hee Kwon; Young Sung Yun; Nam Gyu Lee; Dae-Ghon Kim; Hong Gil Nam; Kwan Yong Choi
Journal:  Clin Exp Metastasis       Date:  2012-08-09       Impact factor: 5.150

Review 6.  Luteolin, a flavonoid with potential for cancer prevention and therapy.

Authors:  Yong Lin; Ranxin Shi; Xia Wang; Han-Ming Shen
Journal:  Curr Cancer Drug Targets       Date:  2008-11       Impact factor: 3.428

7.  ETS1 regulates Twist1 transcription in a KrasG12D/Lkb1-/- metastatic lung tumor model of non-small cell lung cancer.

Authors:  Guetchyn Millien; Yuxia Cao; Carl J O'Hara; Jean-Bosco Tagne; Anne Hinds; Mary C Williams; Maria I Ramirez; Hasmeena Kathuria
Journal:  Clin Exp Metastasis       Date:  2018-06-16       Impact factor: 5.150

Review 8.  Oral epithelial stem cells - implications in normal development and cancer metastasis.

Authors:  Silvana Papagerakis; Giuseppe Pannone; Li Zheng; Imad About; Nawar Taqi; Nghia P T Nguyen; Margarite Matossian; Blake McAlpin; Angela Santoro; Jonathan McHugh; Mark E Prince; Petros Papagerakis
Journal:  Exp Cell Res       Date:  2014-05-05       Impact factor: 3.905

Review 9.  MACC1 - more than metastasis? Facts and predictions about a novel gene.

Authors:  Ulrike Stein; Mathias Dahlmann; Wolfgang Walther
Journal:  J Mol Med (Berl)       Date:  2009-09-30       Impact factor: 4.599

10.  Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

Authors:  Eva A Turley; Mandana Veiseh; Derek C Radisky; Mina J Bissell
Journal:  Nat Clin Pract Oncol       Date:  2008-03-18
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.