Literature DB >> 16645252

Evaluation of imaging performance of a taper optics CCD; FReLoN' camera designed for medical imaging.

Paola Coan1, Angela Peterzol, Stefan Fiedler, Cyril Ponchut, Jean Claude Labiche, Alberto Bravin.   

Abstract

The purpose of this work was to assess the imaging performance of an indirect conversion detector (taper optics CCD; FReLoN' camera) in terms of the modulation transfer function (MTF), normalized noise power spectrum (NNPS) and detective quantum efficiency (DQE). Measurements were made with a synchrotron radiation laminar beam at various monochromatic energies in the 20-51.5 keV range for a gadolinium-based fluorescent screen varying in thickness; data acquisition and analysis were made by adapting to this beam geometry protocols used for conventional cone beams. The pre-sampled MTFs of the systems were measured using an edge method. The NNPS of the systems were determined for a range of exposure levels by two-dimensional Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, NNPS, exposure and incoming number of photons. The MTF, for a given screen, was found to be almost energy independent and, for a given energy, higher for the thinnest screen. At 33 keV and for the 40 (100) microm screen, at 10% the MTF is 9.2 (8.6) line-pairs mm(-1). The NNPS was found to be different in the two analyzed directions in relation to frequency. Highest DQE values were found for the combination 100 microm and 25 keV (0.5); it was still equal to 0.4 at 51.5 keV (above the gadolinium K-edge). The DQE is limited by the phosphor screen conversion yield and by the CCD efficiency. At the end of the manuscript the results of the FReLoN characterization and those from a selected number of detectors presented in the literature are compared.

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Year:  2006        PMID: 16645252     DOI: 10.1107/S0909049506008983

Source DB:  PubMed          Journal:  J Synchrotron Radiat        ISSN: 0909-0495            Impact factor:   2.616


  20 in total

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Journal:  J Digit Imaging       Date:  2014-02       Impact factor: 4.056

2.  Analyzer-based imaging technique in tomography of cartilage and metal implants: a study at the ESRF.

Authors:  Paola Coan; Juergen Mollenhauer; Andreas Wagner; Carol Muehleman; Alberto Bravin
Journal:  Eur J Radiol       Date:  2008-06-26       Impact factor: 3.528

3.  Small-angle solution scattering using the mixed-mode pixel array detector.

Authors:  Lucas J Koerner; Richard E Gillilan; Katherine S Green; Suntao Wang; Sol M Gruner
Journal:  J Synchrotron Radiat       Date:  2010-12-08       Impact factor: 2.616

4.  Deep transfer learning for characterizing chondrocyte patterns in phase contrast X-Ray computed tomography images of the human patellar cartilage.

Authors:  Anas Z Abidin; Botao Deng; Adora M DSouza; Mahesh B Nagarajan; Paola Coan; Axel Wismüller
Journal:  Comput Biol Med       Date:  2018-02-09       Impact factor: 4.589

5.  Volumetric quantitative characterization of human patellar cartilage with topological and geometrical features on phase-contrast X-ray computed tomography.

Authors:  Mahesh B Nagarajan; Paola Coan; Markus B Huber; Paul C Diemoz; Axel Wismüller
Journal:  Med Biol Eng Comput       Date:  2015-07-04       Impact factor: 2.602

6.  Volumetric Characterization of Human Patellar Cartilage Matrix on Phase Contrast X-Ray Computed Tomography.

Authors:  Anas Z Abidin; Mahesh B Nagarajan; Walter A Checefsky; Paola Coan; Paul C Diemoz; Susan K Hobbs; Markus B Huber; Axel Wismüller
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2015-03-19

7.  Computer-aided diagnosis in phase contrast imaging X-ray computed tomography for quantitative characterization of ex vivo human patellar cartilage.

Authors:  Mahesh B Nagarajan; Paola Coan; Markus B Huber; Paul C Diemoz; Christian Glaser; Axel Wismuller
Journal:  IEEE Trans Biomed Eng       Date:  2013-06-05       Impact factor: 4.538

8.  Non-conventional Ultra-High Dose Rate (FLASH) Microbeam Radiotherapy Provides Superior Normal Tissue Sparing in Rat Lung Compared to Non-conventional Ultra-High Dose Rate (FLASH) Radiotherapy.

Authors:  Michael D Wright; Pantaleo Romanelli; Alberto Bravin; Geraldine Le Duc; Elke Brauer-Krisch; Herwig Requardt; Stefan Bartzsch; Ruslan Hlushchuk; Jean-Albert Laissue; Valentin Djonov
Journal:  Cureus       Date:  2021-11-06

9.  High-resolution, low-dose phase contrast X-ray tomography for 3D diagnosis of human breast cancers.

Authors:  Yunzhe Zhao; Emmanuel Brun; Paola Coan; Zhifeng Huang; Aniko Sztrókay; Paul Claude Diemoz; Susanne Liebhardt; Alberto Mittone; Sergei Gasilov; Jianwei Miao; Alberto Bravin
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-22       Impact factor: 11.205

10.  X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.

Authors:  Arne Tapfer; Rickmer Braren; Martin Bech; Marian Willner; Irene Zanette; Timm Weitkamp; Marija Trajkovic-Arsic; Jens T Siveke; Marcus Settles; Michaela Aichler; Axel Walch; Franz Pfeiffer
Journal:  PLoS One       Date:  2013-03-11       Impact factor: 3.240

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