| Literature DB >> 16644237 |
T Austin1, A P Gibson, G Branco, R Md Yusof, S R Arridge, J H Meek, J S Wyatt, D T Delpy, J C Hebden.
Abstract
Optical methods provide a means of monitoring cerebral oxygenation in newborn infants at risk of brain injury. A 32-channel optical imaging system has been developed with the aim of reconstructing three-dimensional images of regional blood volume and oxygenation. Full image data sets were acquired from 14 out of 24 infants studied; successful images have been reconstructed in 8 of these infants. Regional variations in cerebral blood volume and tissue oxygen saturation are present in healthy preterm infants. In an infant with a large unilateral intraventricular haemorrhage, a corresponding region of low oxygen saturation was detected. These results suggest that optical tomography may provide an appropriate technique for investigating regional cerebral haemodynamics and oxygenation at the cotside.Entities:
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Year: 2006 PMID： 16644237 DOI： 10.1016/j.neuroimage.2006.02.038
Source DB: PubMed Journal: Neuroimage ISSN： 1053-8119 Impact factor: 6.556