| Literature DB >> 16643036 |
Stephen T Deyrup1, Dale C Swenson, James B Gloer, Donald T Wicklow.
Abstract
Three new caryophyllene-type sesquiterpene alcohols, 6-hydroxypunctaporonin E (1), 6-hydroxypunctaporonin B (2), and 6-hydroxypunctaporonin A (3), have been isolated from cultures of the fungicolous fungus Pestalotiopsis disseminata. The structures of 1-3 were determined mainly by analysis of 1D and 2D NMR data. The structure and absolute configuration of 6-hydroxypunctaporonin E (1) was confirmed through X-ray crystallographic analysis of its mono-bromobenzoate derivative. Compounds 1 and 2 showed activity against Gram-positive bacteria.Entities:
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Year: 2006 PMID: 16643036 DOI: 10.1021/np050460b
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050