Literature DB >> 16643029

DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii.

Eric H Andrianasolo1, Dennis France, Susan Cornell-Kennon, William H Gerwick.   

Abstract

Three new halogenated monoterpenes, 2, 3, and 4, along with the known compounds halomon (1) and two analogues, 5 and 6, were isolated from the Madagascar red marine alga Portieria hornemannii. The structures of all three new compounds were determined by NMR spectroscopy in combination with mass spectrometric data analysis. Two of these monoterpenes (1 and 2) were low micromolar inhibitors of DNA methyl transferase-1.

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Year:  2006        PMID: 16643029     DOI: 10.1021/np0503956

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  19 in total

1.  Induction of apoptosis by diterpenes from the soft coral Xenia elongata.

Authors:  Eric H Andrianasolo; Liti Haramaty; Kurt Degenhardt; Robin Mathew; Eileen White; Richard Lutz; Paul Falkowski
Journal:  J Nat Prod       Date:  2007-09-28       Impact factor: 4.050

2.  Apoptosis-inducing galactolipids from a cultured marine diatom, Phaeodactylum tricornutum.

Authors:  Eric H Andrianasolo; Liti Haramaty; Assaf Vardi; Eileen White; Richard Lutz; Paul Falkowski
Journal:  J Nat Prod       Date:  2008-06-21       Impact factor: 4.050

3.  Adsorbable organic bromine compounds (AOBr) in aquatic samples: a nematode-based toxicogenomic assessment of the exposure hazard.

Authors:  Nadine Saul; Stephen R Stürzenbaum; Shumon Chakrabarti; Nora Baberschke; Thora Lieke; Anke Putschew; Cindy Kochan; Ralph Menzel; Christian E W Steinberg
Journal:  Environ Sci Pollut Res Int       Date:  2015-05-22       Impact factor: 4.223

Review 4.  The major bioactive components of seaweeds and their mosquitocidal potential.

Authors:  Ke-Xin Yu; Ibrahim Jantan; Rohani Ahmad; Ching-Lee Wong
Journal:  Parasitol Res       Date:  2014-08-14       Impact factor: 2.289

5.  Highly Selective Synthesis of Halomon, Plocamenone, and Isoplocamenone.

Authors:  Cyril Bucher; Richard M Deans; Noah Z Burns
Journal:  J Am Chem Soc       Date:  2015-09-29       Impact factor: 15.419

6.  A novel galacto-glycerolipid from Oxalis corniculata kills Entamoeba histolytica and Giardia lamblia.

Authors:  Dipak Manna; Pradeep K Dutta; Basudeb Achari; Anuradha Lohia
Journal:  Antimicrob Agents Chemother       Date:  2010-08-16       Impact factor: 5.191

7.  Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors.

Authors:  Carl V Vogel; Halina Pietraszkiewicz; Omar M Sabry; William H Gerwick; Frederick A Valeriote; Christopher D Vanderwal
Journal:  Angew Chem Int Ed Engl       Date:  2014-09-12       Impact factor: 15.336

Review 8.  Marine pharmacology in 2005-6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Roberto G S Berlinck; Mark T Hamann
Journal:  Biochim Biophys Acta       Date:  2009-03-19

9.  Variability of non-polar secondary metabolites in the red alga Portieria.

Authors:  Dioli Ann Payo; Joannamel Colo; Hilconida Calumpong; Olivier de Clerck
Journal:  Mar Drugs       Date:  2011-11-21       Impact factor: 6.085

10.  Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay.

Authors:  Jo-Anne de la Mare; Jason N Sterrenberg; Mugdha G Sukhthankar; Maynard T Chiwakata; Denzil R Beukes; Gregory L Blatch; Adrienne L Edkins
Journal:  Cancer Cell Int       Date:  2013-05-01       Impact factor: 5.722

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