Literature DB >> 16641511

Processing body autoantibodies reconsidered.

Donald B Bloch, Tod Gulick, Kenneth D Bloch, Wei-Hong Yang.   

Abstract

Processing bodies (P-bodies) are cellular structures that have critical roles in mRNA degradation and post-transcriptional gene silencing. Some patients with autoimmune disease have high titer antibodies directed against P-bodies, and certain sera have been used as markers for the GW182 component of these structures. This study shows that available reference sera are unreliable markers for GW182 because the sera contain antibodies directed against Ge-1, a second P-body autoantigen.

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Year:  2006        PMID： 16641511      PMCID： PMC1440902          DOI： 10.1261/rna.17406

Source DB:  PubMed          Journal:  RNA        ISSN： 1355-8382            Impact factor:   4.942


  14 in total

1.  Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Authors:  Ujwal Sheth; Roy Parker
Journal:  Science       Date:  2003-05-02       Impact factor: 47.728

2.  Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies.

Authors:  George L Sen; Helen M Blau
Journal:  Nat Cell Biol       Date:  2005-05-22       Impact factor: 28.824

3.  Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

Authors:  Martin Fenger-Grøn; Christy Fillman; Bodil Norrild; Jens Lykke-Andersen
Journal:  Mol Cell       Date:  2005-12-22       Impact factor: 17.970

4.  MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies.

Authors:  Jidong Liu; Marco Antonio Valencia-Sanchez; Gregory J Hannon; Roy Parker
Journal:  Nat Cell Biol       Date:  2005-06-05       Impact factor: 28.824

5.  A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles.

Authors:  Theophany Eystathioy; Edward K L Chan; Scott A Tenenbaum; Jack D Keene; Kevin Griffith; Marvin J Fritzler
Journal:  Mol Biol Cell       Date:  2002-04       Impact factor: 4.138

6.  GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation.

Authors:  Zheng Yang; Andrew Jakymiw; Malcolm R Wood; Theophany Eystathioy; Robert L Rubin; Marvin J Fritzler; Edward K L Chan
Journal:  J Cell Sci       Date:  2004-10-19       Impact factor: 5.285

7.  The cytoplasmic dot staining pattern is detected in a subgroup of patients with primary biliary cirrhosis.

Authors:  Donald B Bloch; Jiang Hong Yu; Wei-Hong Yang; Fiona Graeme-Cook; Keith D Lindor; Anjali Viswanathan; Kenneth D Bloch; Ayako Nakajima
Journal:  J Rheumatol       Date:  2005-03       Impact factor: 4.666

8.  Clinical and serological associations of autoantibodies to GW bodies and a novel cytoplasmic autoantigen GW182.

Authors:  Theophany Eystathioy; Edward K L Chan; Ken Takeuchi; Michael Mahler; LeeAnne M Luft; Douglas W Zochodne; Marvin J Fritzler
Journal:  J Mol Med (Berl)       Date:  2003-11-04       Impact factor: 4.599

9.  The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies.

Authors:  Theophany Eystathioy; Andrew Jakymiw; Edward K L Chan; Bertrand Séraphin; Nicolas Cougot; Marvin J Fritzler
Journal:  RNA       Date:  2003-10       Impact factor: 4.942

10.  Cytoplasmic foci are sites of mRNA decay in human cells.

Authors:  Nicolas Cougot; Sylvie Babajko; Bertrand Séraphin
Journal:  J Cell Biol       Date:  2004-04-05       Impact factor: 10.539
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  8 in total

1.  Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing.

Authors:  Songqing Li; Shang L Lian; Joanna J Moser; Mark L Fritzler; Marvin J Fritzler; Minoru Satoh; Edward K L Chan
Journal:  J Cell Sci       Date:  2008-12-15       Impact factor: 5.285

2.  Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling.

Authors:  Robert A Lindquist; Kathleen A Ottina; Douglas B Wheeler; Peggy P Hsu; Carson C Thoreen; David A Guertin; Siraj M Ali; Shomit Sengupta; Yoav D Shaul; Michael R Lamprecht; Katherine L Madden; Adam R Papallo; Thouis R Jones; David M Sabatini; Anne E Carpenter
Journal:  Genome Res       Date:  2011-01-14       Impact factor: 9.043

3.  Clinical and serological features of patients with autoantibodies to GW/P bodies.

Authors:  Rahima A Bhanji; Theophany Eystathioy; Edward K L Chan; Donald B Bloch; Marvin J Fritzler
Journal:  Clin Immunol       Date:  2007-09-17       Impact factor: 3.969

4.  Processing bodies are not required for mammalian nonsense-mediated mRNA decay.

Authors:  Lukas Stalder; Oliver Mühlemann
Journal:  RNA       Date:  2009-05-27       Impact factor: 4.942

5.  Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity.

Authors:  Derrick J Gibbings; Constance Ciaudo; Mathieu Erhardt; Olivier Voinnet
Journal:  Nat Cell Biol       Date:  2009-08-16       Impact factor: 28.824

6.  P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes.

Authors:  Matyas Flemr; Jun Ma; Richard M Schultz; Petr Svoboda
Journal:  Biol Reprod       Date:  2010-01-14       Impact factor: 4.285

7.  MILI, a PIWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation.

Authors:  Yingdee Unhavaithaya; Yi Hao; Ergin Beyret; Hang Yin; Satomi Kuramochi-Miyagawa; Toru Nakano; Haifan Lin
Journal:  J Biol Chem       Date:  2008-12-29       Impact factor: 5.157

8.  Establishment of international autoantibody reference standards for the detection of autoantibodies directed against PML bodies, GW bodies, and NuMA protein.

Authors:  Bing Zheng; Rodrigo A Mora; Marvin J Fritzler; Minoru Satoh; Donald B Bloch; Ignacio Garcia-De La Torre; Katherine Boylan; Kathryn Kohl; Mark H Wener; Luis E C Andrade; Edward K L Chan
Journal:  Clin Chem Lab Med       Date:  2020-08-10       Impact factor: 3.694
  8 in total

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