Literature DB >> 16641501

Medical management of radiation injuries: current approaches.

M E Berger1, D M Christensen, P C Lowry, O W Jones, A L Wiley.   

Abstract

The current approach to medical management of irradiated patients begins with early diagnosis of radiation injury. Medical assessment of radiation dose is based on event history, symptomatology and laboratory results, with emphasis on time to emesis and lymphocyte depletion kinetics. Dose assessment provides a basis for early use of haematopoietic growth factors that can shorten the period of neutropaenia for patients with acute radiation syndrome. Assessments of haematopoietic, gastrointestinal and cutaneous syndromes have improved in recent years, but treatment options remain limited. Selected examples of current developments are presented.

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Year:  2006        PMID: 16641501     DOI: 10.1093/occmed/kql011

Source DB:  PubMed          Journal:  Occup Med (Lond)        ISSN: 0962-7480            Impact factor:   1.611


  27 in total

Review 1.  Current status of biodosimetry based on standard cytogenetic methods.

Authors:  Marcela Maria Pereira de Lemos Pinto; Neyliane Frassinetti Gonçalves Santos; Ademir Amaral
Journal:  Radiat Environ Biophys       Date:  2010-07-09       Impact factor: 1.925

2.  Toll-like receptor 5 agonist protects mice from dermatitis and oral mucositis caused by local radiation: implications for head-and-neck cancer radiotherapy.

Authors:  Lyudmila G Burdelya; Anatoli S Gleiberman; Ilia Toshkov; Semra Aygun-Sunar; Meghana Bapardekar; Patricia Manderscheid-Kern; David Bellnier; Vadim I Krivokrysenko; Elena Feinstein; Andrei V Gudkov
Journal:  Int J Radiat Oncol Biol Phys       Date:  2011-10-14       Impact factor: 7.038

3.  Case files of the University of Massachusetts fellowship in medical toxicology: three patients with an industrial radiography source exposure.

Authors:  Christina Hernon; Edward W Boyer; Doran Christensen; Steve Sugarman
Journal:  J Med Toxicol       Date:  2006-12

4.  Evaluating the Special Needs of The Military for Radiation Biodosimetry for Tactical Warfare Against Deployed Troops: Comparing Military to Civilian Needs for Biodosimetry Methods.

Authors:  Ann Barry Flood; Arif N Ali; Holly K Boyle; Gaixin Du; Victoria A Satinsky; Steven G Swarts; Benjamin B Williams; Eugene Demidenko; Wilson Schreiber; Harold M Swartz
Journal:  Health Phys       Date:  2016-08       Impact factor: 1.316

5.  A Framework for Comparative Evaluation of Dosimetric Methods to Triage a Large Population Following a Radiological Event.

Authors:  Ann Barry Flood; Roberto J Nicolalde; Eugene Demidenko; Benjamin B Williams; Alla Shapiro; Albert L Wiley; Harold M Swartz
Journal:  Radiat Meas       Date:  2011-09-01       Impact factor: 1.898

Review 6.  Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems.

Authors:  Nicholas Dainiak; Robert Nicolas Gent; Zhanat Carr; Rita Schneider; Judith Bader; Elena Buglova; Nelson Chao; C Norman Coleman; Arnold Ganser; Claude Gorin; Martin Hauer-Jensen; L Andrew Huff; Patricia Lillis-Hearne; Kazuhiko Maekawa; Jeffrey Nemhauser; Ray Powles; Holger Schünemann; Alla Shapiro; Leif Stenke; Nelson Valverde; David Weinstock; Douglas White; Joseph Albanese; Viktor Meineke
Journal:  Disaster Med Public Health Prep       Date:  2011-10-10       Impact factor: 1.385

7.  Advances in a framework to compare bio-dosimetry methods for triage in large-scale radiation events.

Authors:  Ann Barry Flood; Holly K Boyle; Gaixin Du; Eugene Demidenko; Roberto J Nicolalde; Benjamin B Williams; Harold M Swartz
Journal:  Radiat Prot Dosimetry       Date:  2014-04-11       Impact factor: 0.972

Review 8.  Advances in in vivo EPR Tooth BIOdosimetry: Meeting the targets for initial triage following a large-scale radiation event.

Authors:  Ann Barry Flood; Benjamin B Williams; Wilson Schreiber; Gaixin Du; Victoria A Wood; Maciej M Kmiec; Sergey V Petryakov; Eugene Demidenko; Harold M Swartz
Journal:  Radiat Prot Dosimetry       Date:  2016-07-15       Impact factor: 0.972

9.  GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.

Authors:  Peng Li; Evan Wuthrick; Jeff A Rappaport; Crystal Kraft; Jieru E Lin; Glen Marszalowicz; Adam E Snook; Tingting Zhan; Terry M Hyslop; Scott A Waldman
Journal:  Cancer Res       Date:  2017-09-15       Impact factor: 12.701

10.  Combined Therapy of Pegylated G-CSF and Alxn4100TPO Improves Survival and Mitigates Acute Radiation Syndrome after Whole-Body Ionizing Irradiation Alone and Followed by Wound Trauma.

Authors:  Juliann G Kiang; Min Zhai; David L Bolduc; Joan T Smith; Marsha N Anderson; Connie Ho; Bin Lin; Suping Jiang
Journal:  Radiat Res       Date:  2017-08-29       Impact factor: 2.841

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