| Literature DB >> 16636253 |
M Longoni1, C Grond-Ginsbach, A J Grau, J Genius, S Debette, M Schwaninger, C Ferrarese, C Lichy.
Abstract
In a primary study on proinflammatory genetic profiles in stroke, the authors found the E469K polymorphism of the intercellular adhesion molecule 1 (ICAM-1) highly represented in the subgroup with spontaneous cervical artery dissection (sCAD). They further investigated the same genetic variant in a second group of 65 patients with sCAD. An association between sCAD and EE genotype was confirmed (odds ratio 3.16; p < 0.01), indicating that a proinflammatory predisposition is a risk factor for sCAD.Entities:
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Year: 2006 PMID: 16636253 DOI: 10.1212/01.wnl.0000208411.01172.0b
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910