Literature DB >> 16635434

Role of mitochondria in multiple sclerosis.

Bernadette Kalman1.   

Abstract

This review presents inherited and acquired forms of mitochondrial dysfunction associated with oligodendrocytopathy and neurodegeneration in order to better understand the degenerative features of inflammatory demyelination. The recognition that various mitochondrial mechanisms are involved in the pathogenesis of multiple sclerosis leads to therapeutic considerations, re-emphasizing the importance of early neuroprotection in combination with the approved means of immune modulation.

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Year:  2006        PMID： 16635434     DOI： 10.1007/s11910-006-0012-0

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN： 1528-4042            Impact factor:   5.081


  51 in total

1.  Suppression of complex I gene expression induces optic neuropathy.

Authors:  Xiaoping Qi; Alfred S Lewin; William W Hauswirth; John Guy
Journal:  Ann Neurol       Date:  2003-02       Impact factor: 10.422

2.  Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination.

Authors:  C Lucchinetti; W Brück; J Parisi; B Scheithauer; M Rodriguez; H Lassmann
Journal:  Ann Neurol       Date:  2000-06       Impact factor: 10.422

Review 3.  Mitochondrial encephalomyopathies: an update.

Authors:  Salvatore DiMauro; Michio Hirano
Journal:  Neuromuscul Disord       Date:  2005-04       Impact factor: 4.296

4.  Sequence and organization of the human mitochondrial genome.

Authors:  S Anderson; A T Bankier; B G Barrell; M H de Bruijn; A R Coulson; J Drouin; I C Eperon; D P Nierlich; B A Roe; F Sanger; P H Schreier; A J Smith; R Staden; I G Young
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

5.  Evidence for the production of peroxynitrite in inflammatory CNS demyelination.

Authors:  A H Cross; P T Manning; M K Stern; T P Misko
Journal:  J Neuroimmunol       Date:  1997-12       Impact factor: 3.478

6.  Parent-child concordance in multiple sclerosis.

Authors:  A D Sadovnick; D Bulman; G C Ebers
Journal:  Ann Neurol       Date:  1991-03       Impact factor: 10.422

7.  Neuropathology of white matter disease in Leber's hereditary optic neuropathy.

Authors:  Gábor G Kovács; Romana Höftberger; Katalin Majtényi; Rita Horváth; Péter Barsi; Sámuel Komoly; Hans Lassmann; Herbert Budka; Gábor Jakab
Journal:  Brain       Date:  2004-10-13       Impact factor: 13.501

8.  Oxidative damage to DNA in plaques of MS brains.

Authors:  O Vladimirova; J O'Connor; A Cahill; H Alder; C Butunoi; B Kalman
Journal:  Mult Scler       Date:  1998-10       Impact factor: 6.312

9.  Severe impairment of complex I-driven adenosine triphosphate synthesis in leber hereditary optic neuropathy cybrids.

Authors:  Alessandra Baracca; Giancarlo Solaini; Gianluca Sgarbi; Giorgio Lenaz; Agostino Baruzzi; Anthony H V Schapira; Andrea Martinuzzi; Valerio Carelli
Journal:  Arch Neurol       Date:  2005-05

10.  Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency.

Authors:  V Tiranti; K Hoertnagel; R Carrozzo; C Galimberti; M Munaro; M Granatiero; L Zelante; P Gasparini; R Marzella; M Rocchi; M P Bayona-Bafaluy; J A Enriquez; G Uziel; E Bertini; C Dionisi-Vici; B Franco; T Meitinger; M Zeviani
Journal:  Am J Hum Genet       Date:  1998-12       Impact factor: 11.025
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  8 in total

1.  NADH-dehydrogenase type-2 suppresses irreversible visual loss and neurodegeneration in the EAE animal model of MS.

Authors:  Venu Talla; Hong Yu; Tsung-Han Chou; Vittorio Porciatti; Vince Chiodo; Sanford L Boye; William W Hauswirth; Alfred S Lewin; John Guy
Journal:  Mol Ther       Date:  2013-06-11       Impact factor: 11.454

2.  Complex I subunit gene therapy with NDUFA6 ameliorates neurodegeneration in EAE.

Authors:  Venu Talla; Rajeshwari Koilkonda; Vittorio Porciatti; Vince Chiodo; Sanford L Boye; William W Hauswirth; John Guy
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-01-22       Impact factor: 4.799

3.  Lack of mitochondrial DNA deletions in lesions of multiple sclerosis.

Authors:  Andrei Blokhin; Tamara Vyshkina; Samuel Komoly; Bernadette Kalman
Journal:  Neuromolecular Med       Date:  2008       Impact factor: 3.843

4.  Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus.

Authors:  Tamara Vyshkina; Andrew Sylvester; Saud Sadiq; Eduardo Bonilla; Jeff A Canter; Andras Perl; Bernadette Kalman
Journal:  Clin Immunol       Date:  2008-08-16       Impact factor: 3.969

5.  MRI characteristics of patients with antiphospholipid syndrome and multiple sclerosis.

Authors:  Milena Stosic; Julian Ambrus; Neeta Garg; Bianca Weinstock-Guttman; Murali Ramanathan; Bernadette Kalman; Alireza Minagar; Frederick E Munschauer; Timothy M Galey; Sara Hussein; Rohit Bakshi; Robert Zivadinov
Journal:  J Neurol       Date:  2009-07-26       Impact factor: 4.849

6.  Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains.

Authors:  Xinhua Yu; Ulrike Gimsa; Lena Wester-Rosenlöf; Ellen Kanitz; Winfried Otten; Manfred Kunz; Saleh M Ibrahim
Journal:  Genome Res       Date:  2008-11-26       Impact factor: 9.043

7.  Gene Therapy with Single-Subunit Yeast NADH-Ubiquinone Oxidoreductase (NDI1) Improves the Visual Function in Experimental Autoimmune Encephalomyelitis (EAE) Mice Model of Multiple Sclerosis (MS).

Authors:  Venu Talla; Rajeshwari Koilkonda; John Guy
Journal:  Mol Neurobiol       Date:  2020-01-03       Impact factor: 5.590

8.  Mitochondrial DNA haplogroup T is associated with coronary artery disease and diabetic retinopathy: a case control study.

Authors:  Barbara Kofler; Edith E Mueller; Waltraud Eder; Olaf Stanger; Richard Maier; Martin Weger; Anton Haas; Robert Winker; Otto Schmut; Bernhard Paulweber; Bernhard Iglseder; Wilfried Renner; Martina Wiesbauer; Irene Aigner; Danijela Santic; Franz A Zimmermann; Johannes A Mayr; Wolfgang Sperl
Journal:  BMC Med Genet       Date:  2009-04-21       Impact factor: 2.103
  8 in total

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