D Doherty1, S Tu, K Schilmoeller, G Schilmoeller. 1. College of Education and Human Development, University of Maine, Orono, ME 04469-5749, USA. dona.doherty@umit.maine.edu
Abstract
OBJECTIVES: To explore and compare the prevalence and expression of specific health-related variables in a large survey sample of persons with agenesis of the corpus callosum (ACC) and their siblings. METHODS: Caregiver surveys of individuals with ACC (n=189) and their siblings (n=189) provided data regarding diagnoses, physical features, neurological and sensory information, feeding, elimination and sleep concerns, and some behavioural features. RESULTS: Compared with their siblings, individuals with ACC had more concurrent conditions and were more likely to have altered pain perception and sensitivity to touch. In addition, individuals with ACC had more sensory deficits and abnormalities as well as altered patterns of feeding/eating, elimination and sleep. CONCLUSIONS: These data raise important questions for future research and suggest the need for increased vigilance by caregivers and health-care professionals of individuals with callosal disorders. Early detection and intervention may help prevent or ameliorate health problems in this population.
OBJECTIVES: To explore and compare the prevalence and expression of specific health-related variables in a large survey sample of persons with agenesis of the corpus callosum (ACC) and their siblings. METHODS: Caregiver surveys of individuals with ACC (n=189) and their siblings (n=189) provided data regarding diagnoses, physical features, neurological and sensory information, feeding, elimination and sleep concerns, and some behavioural features. RESULTS: Compared with their siblings, individuals with ACC had more concurrent conditions and were more likely to have altered pain perception and sensitivity to touch. In addition, individuals with ACC had more sensory deficits and abnormalities as well as altered patterns of feeding/eating, elimination and sleep. CONCLUSIONS: These data raise important questions for future research and suggest the need for increased vigilance by caregivers and health-care professionals of individuals with callosal disorders. Early detection and intervention may help prevent or ameliorate health problems in this population.
Authors: Brittany G Travers; Nagesh Adluru; Chad Ennis; Do P M Tromp; Dan Destiche; Sam Doran; Erin D Bigler; Nicholas Lange; Janet E Lainhart; Andrew L Alexander Journal: Autism Res Date: 2012-07-11 Impact factor: 5.216
Authors: Tomasz A Jarczok; Merve Fritsch; Anne Kröger; Anna Lisa Schneider; Heike Althen; Michael Siniatchkin; Christine M Freitag; Stephan Bender Journal: J Neural Transm (Vienna) Date: 2016-05-13 Impact factor: 3.575
Authors: Yolanda C Lau; Leighton B N Hinkley; Polina Bukshpun; Zoe A Strominger; Mari L J Wakahiro; Simon Baron-Cohen; Carrie Allison; Bonnie Auyeung; Rita J Jeremy; Srikantan S Nagarajan; Elliott H Sherr; Elysa J Marco Journal: J Autism Dev Disord Date: 2013-05
Authors: Chayim Can Schell-Apacik; Kristina Wagner; Moritz Bihler; Birgit Ertl-Wagner; Uwe Heinrich; Eva Klopocki; Vera M Kalscheuer; Maximilian Muenke; Hubertus von Voss Journal: Am J Med Genet A Date: 2008-10-01 Impact factor: 2.802
Authors: Denise H Badaruddin; Glena L Andrews; Sven Bölte; Kathryn J Schilmoeller; Gary Schilmoeller; Lynn K Paul; Warren S Brown Journal: Child Psychiatry Hum Dev Date: 2007-06-13