| Literature DB >> 1662643 |
E Grazi1, E Magri, P Cuneo, A Cataldi.
Abstract
Solation of actin gel by gelsolin is much less efficient in the presence of a high concentration of macromolecular solutes. The rigidity of the gel formed by 12 microM actin is lowered from 4 to 0.33 dynes/cm2 by 15 nM gelsolin, while in 6% (w/v) polyethylene glycol, rigidity is lowered only from 20 to 11 dynes/cm2 by 64 nM gelsolin. Owing to the large concentration of protein, transitions in the fluid- and gel-like properties of the cytoplasm are expected to be problematic when promoted by gelsolin alone.Entities:
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Year: 1991 PMID： 1662643 DOI： 10.1016/0014-5793(91)81409-2
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124