Literature DB >> 16619664

Intraorbital implantation of a stimulating electrode for an optic nerve visual prosthesis. Case report.

Mårten E Brelén1, Patrick De Potter, Michel Gersdorff, Guy Cosnard, Claude Veraart, Jean Delbeke.   

Abstract

Research into visual prosthetics is expected to revolutionize the treatment of blind patients with incurable outer retinal degenerative disease. Substantial evidence shows that useful visual sensations can be produced by controlled electrical stimulation of the optic nerve. To make the optic nerve visual prosthesis more acceptable, implantation techniques safer and less invasive than those previously used have been developed. A medial transconjunctival approach is now used to implant a stimulating electrode around the intraorbital section of the optic nerve. This new technique allows sufficient exposure of the nerve after detaching only one rectus muscle and performing a lateral canthotomy. Previously, an electrode was implanted in the intracranial part of the optic nerve, which required more invasive surgery. The new technique was first developed in cadavers and in patients undergoing eye enucleations. Finally, a 68-year-old blind man suffering from retinitis pigmentosa underwent long-term implantation. In this case report the authors describe the technique and outline some of the challenges involved.

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Year:  2006        PMID: 16619664     DOI: 10.3171/jns.2006.104.4.593

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  8 in total

1.  Properties of electrically evoked potentials activated by optic nerve stimulation with penetrating electrodes of different modes in rabbits.

Authors:  Pengjia Cao; Jingjing Sun; Yan Yan; Yao Chen; Xinyu Chai; Xiaodong Sun; Qiushi Ren; Liming Li
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-07-31       Impact factor: 3.117

2.  Penetrating electrode stimulation of the rabbit optic nerve: parameters and effects on evoked cortical potentials.

Authors:  Jingjing Sun; Yao Chen; Xinyu Chai; Qiushi Ren; Liming Li
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-09-08       Impact factor: 3.117

Review 3.  Getting signals into the brain: visual prosthetics through thalamic microstimulation.

Authors:  John S Pezaris; Emad N Eskandar
Journal:  Neurosurg Focus       Date:  2009-07       Impact factor: 4.047

4.  Optic nerve potentials and cortical potentials after stimulation of the anterior visual pathway during neurosurgery.

Authors:  Mitja Benedičič; Roman Bošnjak
Journal:  Doc Ophthalmol       Date:  2011-03-16       Impact factor: 2.379

Review 5.  Technology insight: neuroengineering and epilepsy-designing devices for seizure control.

Authors:  William C Stacey; Brian Litt
Journal:  Nat Clin Pract Neurol       Date:  2008-02-26

6.  Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment.

Authors:  Yikui Zhang; Shengjian Lu; Shenghai Huang; Zhonghao Yu; Tian Xia; Mengyun Li; Chen Yang; Yiyang Mao; Boyue Xu; Lixu Wang; Lei Xu; Jieliang Shi; Xingfang Zhu; Senmiao Zhu; Si Zhang; Haohua Qian; Yang Hu; Wei Li; Yunhai Tu; Wencan Wu
Journal:  Theranostics       Date:  2022-04-11       Impact factor: 11.600

Review 7.  Contemporary approaches to visual prostheses.

Authors:  Rebecca M Mirochnik; John S Pezaris
Journal:  Mil Med Res       Date:  2019-06-05

8.  Optoelectronic Devices for Vision Restoration.

Authors:  Victor Wang; Ajay E Kuriyan
Journal:  Curr Ophthalmol Rep       Date:  2020-04-20
  8 in total

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