Literature DB >> 16611574

Is kinetoplastid pan-editing the result of an evolutionary balancing act?

Dave Speijer1.   

Abstract

Kinetoplastid U-insertion/deletion type editing is a highly elaborate process to generate translationally competent mitochondrial mRNAs. All evolutionary models to explain its origin and extent in present day organisms lack a convincing description of the advantage(s) responsible for an active increase of the editing potential. This advantage can be found in the gene fragmentation that is inherent in pan-editing which gives protection against loss of temporarily non expressed mitochondrial genes during periods of intense intraspecies competition.

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Year:  2006        PMID: 16611574     DOI: 10.1080/15216540600551355

Source DB:  PubMed          Journal:  IUBMB Life        ISSN: 1521-6543            Impact factor:   3.885


  11 in total

Review 1.  Gene fragmentation: a key to mitochondrial genome evolution in Euglenozoa?

Authors:  Pavel Flegontov; Michael W Gray; Gertraud Burger; Julius Lukeš
Journal:  Curr Genet       Date:  2011-05-05       Impact factor: 3.886

2.  Constructive neutral evolution cannot explain current kinetoplastid panediting patterns.

Authors:  Dave Speijer
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-09       Impact factor: 11.205

3.  Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool.

Authors:  Evgeny S Gerasimov; Anna A Gasparyan; Iosif Kaurov; Boris Tichý; Maria D Logacheva; Alexander A Kolesnikov; Julius Lukeš; Vyacheslav Yurchenko; Sara L Zimmer; Pavel Flegontov
Journal:  Nucleic Acids Res       Date:  2018-01-25       Impact factor: 16.971

4.  Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei.

Authors:  Lucie Kafková; Michelle L Ammerman; Drahomíra Faktorová; John C Fisk; Sara L Zimmer; Roman Sobotka; Laurie K Read; Julius Lukes; Hassan Hashimi
Journal:  RNA       Date:  2012-08-16       Impact factor: 4.942

5.  Evolution of dyskinetoplastic trypanosomes: how, and how often?

Authors:  Achim Schnaufer
Journal:  Trends Parasitol       Date:  2010-12

Review 6.  Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex.

Authors:  Hassan Hashimi; Sara L Zimmer; Michelle L Ammerman; Laurie K Read; Julius Lukeš
Journal:  Trends Parasitol       Date:  2013-01-08

7.  Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes.

Authors:  W-Matthias Leeder; Niklas F C Hummel; H Ulrich Göringer
Journal:  Sci Rep       Date:  2016-07-20       Impact factor: 4.379

8.  Cell-line specific RNA editing patterns in Trypanosoma brucei suggest a unique mechanism to generate protein variation in a system intolerant to genetic mutations.

Authors:  Laura E Kirby; Donna Koslowsky
Journal:  Nucleic Acids Res       Date:  2020-02-20       Impact factor: 16.971

9.  Mitochondrial dual-coding genes in Trypanosoma brucei.

Authors:  Laura E Kirby; Donna Koslowsky
Journal:  PLoS Negl Trop Dis       Date:  2017-10-09

10.  Massive mitochondrial DNA content in diplonemid and kinetoplastid protists.

Authors:  Julius Lukeš; Richard Wheeler; Dagmar Jirsová; Vojtěch David; John M Archibald
Journal:  IUBMB Life       Date:  2018-10-06       Impact factor: 3.885

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