Literature DB >> 16601645

Characteristics of adolescents and young adults with ADHD who divert or misuse their prescribed medications.

Timothy E Wilens1, Martin Gignac, Allison Swezey, Michael C Monuteaux, Joseph Biederman.   

Abstract

OBJECTIVE: Little is known about the risks and characteristics of attention-deficit/hyperactivity disorder (ADHD) patients who misuse or divert their stimulant medications. As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period.
METHOD: Structured psychiatric interviews for diagnosis and a self-report questionnaire regarding medication use in medicated subjects with ADHD compared with controls without ADHD receiving psychotropics for non-ADHD treatment were employed.
RESULTS: Of 98 subjects receiving psychotropic medications (mean age of 20.8 +/- 5 years), 55 (56%) were ADHD subjects and 43 (44%) were controls receiving medications for other purposes. The authors found that 11% of the ADHD group reported selling their medications compared with no subjects in the control group (z = 0.00, p <.05). An additional 22% of the ADHD group reported misusing their medications compared with 5% of the control subjects (z = 1.7 p =.09) and that those with conduct or substance use disorders accounted for the misuse and diversion. A minority of subjects reported escalating their doses and concomitant use with alcohol and drugs.
CONCLUSIONS: The data indicate that the majority of ADHD individuals, particularly those without conduct or substance use disorders, use their medications appropriately. The authors' findings also highlight the need to monitor medication use in ADHD individuals with conduct and/or substance use disorders and to carefully select agents with a low likelihood of diversion or misuse in this group.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16601645     DOI: 10.1097/01.chi.0000199027.68828.b3

Source DB:  PubMed          Journal:  J Am Acad Child Adolesc Psychiatry        ISSN: 0890-8567            Impact factor:   8.829


  65 in total

1.  Nonmedical prescription stimulant use among college students: why we need to do something and what we need to do.

Authors:  Amelia M Arria; Robert L DuPont
Journal:  J Addict Dis       Date:  2010-10

Review 2.  Understanding attention-deficit/hyperactivity disorder from childhood to adulthood.

Authors:  Timothy E Wilens; Thomas J Spencer
Journal:  Postgrad Med       Date:  2010-09       Impact factor: 3.840

3.  Caffeinated energy drinks in children.

Authors:  Ran D Goldman
Journal:  Can Fam Physician       Date:  2013-09       Impact factor: 3.275

4.  Extended-release medications for children and adolescents with attention-deficit hyperactivity disorder.

Authors:  M Feldman; S Bélanger
Journal:  Paediatr Child Health       Date:  2009-11       Impact factor: 2.253

5.  Sharing and selling of prescription medications in a college student sample.

Authors:  Laura M Garnier; Amelia M Arria; Kimberly M Caldeira; Kathryn B Vincent; Kevin E O'Grady; Eric D Wish
Journal:  J Clin Psychiatry       Date:  2010-03       Impact factor: 4.384

Review 6.  Pharmacokinetic variability of long-acting stimulants in the treatment of children and adults with attention-deficit hyperactivity disorder.

Authors:  James C Ermer; Ben A Adeyi; Michael L Pucci
Journal:  CNS Drugs       Date:  2010-12       Impact factor: 5.749

7.  An application of analyzing the trajectories of two disorders: A parallel piecewise growth model of substance use and attention-deficit/hyperactivity disorder.

Authors:  Mary Rose Mamey; Celestina Barbosa-Leiker; Sterling McPherson; G Leonard Burns; Craig Parks; John Roll
Journal:  Exp Clin Psychopharmacol       Date:  2015-09-21       Impact factor: 3.157

8.  ADHD, Conduct Disorder, Substance Use Disorder, and Nonprescription Stimulant Use.

Authors:  Judith S Brook; Elinor B Balka; Chenshu Zhang; David W Brook
Journal:  J Atten Disord       Date:  2014-04-28       Impact factor: 3.256

9.  Oral administration of (+/-)3,4-methylenedioxymethamphetamine and (+)methamphetamine alters temperature and activity in rhesus macaques.

Authors:  Rebecca D Crean; Sophia A Davis; Michael A Taffe
Journal:  Pharmacol Biochem Behav       Date:  2007-04-03       Impact factor: 3.533

10.  Metabolism, distribution and elimination of lisdexamfetamine dimesylate: open-label, single-centre, phase I study in healthy adult volunteers.

Authors:  Suma M Krishnan; Michael Pennick; Jeffrey G Stark
Journal:  Clin Drug Investig       Date:  2008       Impact factor: 2.859

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.