A novel air filtration delivery system improves seasonal allergic rhinitis.

Twenty percent of the United States population has respiratory allergies. The preferable treatment for allergies is avoidance. Bedrooms offer the best opportunity for allergen avoidance. Most previous studies of air filtration only measured the effect on allergen particle counts, but few have addressed the clinical efficacy. This study measured the effects of a novel laminar flow air filtration device (PureNight) on seasonal ragweed allergies. Seventy-seven percent of the subjects improved significantly on symptom scores, an average of 26% improvement in the morning and 24% in the evening. Daytime sleepiness and quality of life scores also improved significantly in all subjects. Tolerability was excellent. The PureNight device provided significant clinical improvement of allergic symptoms during ragweed hay fever season.