| Literature DB >> 16597151 |
Lyn H Jones1, Thomas Dupont, Charles E Mowbray, Sandra D Newman.
Abstract
[reaction: see text] A concise and efficient route to the construction of a 5-aryloxyimidazole has been developed. The key step was the selective O-arylation of a 2,4-dimethoxybenzyl-protected imidazolone. The final compound is a potent inhibitor of HIV reverse transcriptase.Entities:
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Year: 2006 PMID： 16597151 DOI： 10.1021/ol060316x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005