Literature DB >> 1658941

A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.

H Jüppner1, A B Abou-Samra, M Freeman, X F Kong, E Schipani, J Richards, L F Kolakowski, J Hock, J T Potts, H M Kronenberg.   

Abstract

The complementary DNA encoding a 585-amino acid parathyroid hormone-parathyroid hormone-related peptide (PTH-PTHrP) receptor with seven potential membrane-spanning domains was cloned by COS-7 expression using an opossum kidney cell complementary DNA (cDNA) library. The expressed receptor binds PTH and PTHrP with equal affinity, and both ligands equivalently stimulate adenylate cyclase. Striking homology with the calcitonin receptor and lack of homology with other G protein-linked receptors indicate that receptors for these calcium-regulating hormones are related and represent a new family.

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Year:  1991        PMID： 1658941     DOI： 10.1126/science.1658941

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  204 in total

Review 1.  Calcitonin and calcitonin receptors: bone and beyond.

Authors:  M Pondel
Journal:  Int J Exp Pathol       Date:  2000-12       Impact factor: 1.925

Review 2.  Interaction of PTH and PTHrP with their receptors.

Authors:  T J Gardella; H Jüppner
Journal:  Rev Endocr Metab Disord       Date:  2000-11       Impact factor: 6.514

Review 3.  PTH and PTHrP effects on the skeleton.

Authors:  A C Karaplis; D Goltzman
Journal:  Rev Endocr Metab Disord       Date:  2000-11       Impact factor: 6.514

4.  Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception.

Authors:  Arpad Dobolyi; Hiroshi Ueda; Hitoshi Uchida; Miklós Palkovits; Ted B Usdin
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-29       Impact factor: 11.205

5.  A case of parathyroid hormone-related peptide producing gallbladder carcinoma and establishment of a cell line, PTHrP-GBK.

Authors:  Hirotoshi Ebinuma; Hiroyuki Imaeda; Yukiko Fukuda; Shingo Miyaguchi; Toshiyuki Yasui; Tatsuo Hoshino; Takashi Okamura; Rokuro Ariwa; Hidetsugu Saito
Journal:  Dig Dis Sci       Date:  2002-01       Impact factor: 3.199

Review 6.  The PTH/PTHrP receptor in Jansen's metaphyseal chondrodysplasia.

Authors:  L M Calvi; E Schipani
Journal:  J Endocrinol Invest       Date:  2000-09       Impact factor: 4.256

7.  Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme.

Authors:  Minoti Hiremath; Pamela Dann; Jennifer Fischer; Daniela Butterworth; Kata Boras-Granic; Julie Hens; Joshua Van Houten; Wei Shi; John Wysolmerski
Journal:  Development       Date:  2012-10-03       Impact factor: 6.868

8.  Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor.

Authors:  Dibyendu Kumar Panda; David Goltzman; Andrew C Karaplis
Journal:  Am J Physiol Endocrinol Metab       Date:  2012-10-23       Impact factor: 4.310

9.  Expression of parathyroid hormone receptors in MDCK and LLC-PK1 cells.

Authors:  G Hayes; J Forgo; F R Bringhurst; G Segre; H Murer
Journal:  Pflugers Arch       Date:  1995-09       Impact factor: 3.657

10.  Signaling by N- and C-terminal sequences of parathyroid hormone-related protein in hippocampal neurons.

Authors:  S Fukayama; A H Tashjian; J N Davis; J C Chisholm
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205
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