Literature DB >> 11706746

Interaction of PTH and PTHrP with their receptors.

T J Gardella1, H Jüppner.   

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Year:  2000        PMID： 11706746     DOI： 10.1023/a:1026522619828

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


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  78 in total

1.  A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide.

Authors:  H Jüppner; A B Abou-Samra; M Freeman; X F Kong; E Schipani; J Richards; L F Kolakowski; J Hock; J T Potts; H M Kronenberg
Journal:  Science       Date:  1991-11-15       Impact factor: 47.728

2.  Transmembrane residues of the parathyroid hormone (PTH)/PTH-related peptide receptor that specifically affect binding and signaling by agonist ligands.

Authors:  T J Gardella; M D Luck; M H Fan; C Lee
Journal:  J Biol Chem       Date:  1996-05-31       Impact factor: 5.157

3.  Constitutive activation of the cyclic adenosine 3',5'-monophosphate signaling pathway by parathyroid hormone (PTH)/PTH-related peptide receptors mutated at the two loci for Jansen's metaphyseal chondrodysplasia.

Authors:  E Schipani; G S Jensen; J Pincus; R A Nissenson; T J Gardella; H Jüppner
Journal:  Mol Endocrinol       Date:  1997-06

4.  The N-terminal region of the third intracellular loop of the parathyroid hormone (PTH)/PTH-related peptide receptor is critical for coupling to cAMP and inositol phosphate/Ca2+ signal transduction pathways.

Authors:  Z Huang; Y Chen; S Pratt; T H Chen; T Bambino; R A Nissenson; D M Shoback
Journal:  J Biol Chem       Date:  1996-12-27       Impact factor: 5.157

5.  Binding domain of human parathyroid hormone receptor: from conformation to function.

Authors:  M Pellegrini; A Bisello; M Rosenblatt; M Chorev; D F Mierke
Journal:  Biochemistry       Date:  1998-09-15       Impact factor: 3.162

6.  Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors.

Authors:  T J Gardella; M D Luck; G S Jensen; E Schipani; J T Potts; H Jüppner
Journal:  Endocrinology       Date:  1996-09       Impact factor: 4.736

7.  Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies.

Authors:  A Bisello; A E Adams; D F Mierke; M Pellegrini; M Rosenblatt; L J Suva; M Chorev
Journal:  J Biol Chem       Date:  1998-08-28       Impact factor: 5.157

8.  Analogues of parathyroid hormone modified at positions 3 and 6. Effects on receptor binding and activation of adenylyl cyclase in kidney and bone.

Authors:  F E Cohen; G J Strewler; M S Bradley; M Carlquist; M Nilsson; M Ericsson; T L Ciardelli; R A Nissenson
Journal:  J Biol Chem       Date:  1991-01-25       Impact factor: 5.157

9.  Histidine at position 5 is the specificity "switch" between two parathyroid hormone receptor subtypes.

Authors:  V Behar; C Nakamoto; Z Greenberg; A Bisello; L J Suva; M Rosenblatt; M Chorev
Journal:  Endocrinology       Date:  1996-10       Impact factor: 4.736

10.  Analysis of parathyroid hormone's principal receptor-binding region by site-directed mutagenesis and analog design.

Authors:  T J Gardella; A K Wilson; H T Keutmann; R Oberstein; J T Potts; M Kronenberg; S R Nussbaum
Journal:  Endocrinology       Date:  1993-05       Impact factor: 4.736
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  12 in total

1.  Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation.

Authors:  Augen A Pioszak; Kaleeckal G Harikumar; Naomi R Parker; Laurence J Miller; H Eric Xu
Journal:  J Biol Chem       Date:  2010-02-19       Impact factor: 5.157

2.  Development of a rat parathyroid hormone 2 receptor antagonist.

Authors:  Jonathan Kuo; Ted B Usdin
Journal:  Peptides       Date:  2007-01-04       Impact factor: 3.750

Review 3.  Emerging paradigms in GPCR allostery: implications for drug discovery.

Authors:  Denise Wootten; Arthur Christopoulos; Patrick M Sexton
Journal:  Nat Rev Drug Discov       Date:  2013-08       Impact factor: 84.694

4.  Safety, tolerability and pharmacokinetic study of recombinant human parathyroid hormone [rhPTH (1-84)] in Chinese healthy volunteers.

Authors:  Qian Li; Jian Qiao; Jungang Deng; Tianshu Zeng; Piqi Zhou; Weiyong Li
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2009-08-07

5.  Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening.

Authors:  Cassandra Koole; Denise Wootten; John Simms; Celine Valant; Rohan Sridhar; Owen L Woodman; Laurence J Miller; Roger J Summers; Arthur Christopoulos; Patrick M Sexton
Journal:  Mol Pharmacol       Date:  2010-06-14       Impact factor: 4.436

6.  Recombinant production of TEV cleaved human parathyroid hormone.

Authors:  Christopher O Audu; Jared C Cochran; Maria Pellegrini; Dale F Mierke
Journal:  J Pept Sci       Date:  2013-06-23       Impact factor: 1.905

7.  Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor.

Authors:  Christoph Klenk; Thorsten Vetter; Alexander Zürn; Jean-Pierre Vilardaga; Peter A Friedman; Bin Wang; Martin J Lohse
Journal:  J Biol Chem       Date:  2010-07-23       Impact factor: 5.157

8.  Duplicated zebrafish co-orthologs of parathyroid hormone-related peptide (PTHrP, Pthlh) play different roles in craniofacial skeletogenesis.

Authors:  Yi-Lin Yan; Poulomi Bhattacharya; Xin Jun He; Bhaskar Ponugoti; Ben Marquardt; Jason Layman; Melissa Grunloh; John H Postlethwait; David A Rubin
Journal:  J Endocrinol       Date:  2012-07-03       Impact factor: 4.286

9.  Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.

Authors:  Augen A Pioszak; Naomi R Parker; Thomas J Gardella; H Eric Xu
Journal:  J Biol Chem       Date:  2009-08-12       Impact factor: 5.157

10.  Molecular recognition of parathyroid hormone by its G protein-coupled receptor.

Authors:  Augen A Pioszak; H Eric Xu
Journal:  Proc Natl Acad Sci U S A       Date:  2008-03-28       Impact factor: 11.205
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