Literature DB >> 1658797

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.

P Leroy1, H Nakshatri, P Chambon.   

Abstract

We have characterized the promoter of the mouse retinoic acid receptor alpha 2 (mRAR-alpha 2) isoform. This promoter contains a retinoic acid response element (RARE) that closely resembles the RARE that is present in the RAR-beta 2 promoter. Moreover, RAR-alpha 2 and RAR-beta 2 proximal promoter sequences are similar to each other and generate transcripts whose respective start sites are located at similar positions. The RAR-alpha 2 RARE consists of two directly repeated 5'-GTTCA-3' motifs to which all three RARs (alpha, beta, and gamma) bind in vitro.

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Year:  1991        PMID： 1658797      PMCID： PMC52883          DOI： 10.1073/pnas.88.22.10138

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  21 in total

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Authors:  S Perrin; G Gilliland
Journal:  Nucleic Acids Res       Date:  1990-12-25       Impact factor: 16.971

2.  Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha).

Authors:  N J Brand; M Petkovich; P Chambon
Journal:  Nucleic Acids Res       Date:  1990-12-11       Impact factor: 16.971

3.  A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter.

Authors:  B Hoffmann; J M Lehmann; X K Zhang; T Hermann; M Husmann; G Graupner; M Pfahl
Journal:  Mol Endocrinol       Date:  1990-11

4.  Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex.

Authors:  M P Gaub; M Bellard; I Scheuer; P Chambon; P Sassone-Corsi
Journal:  Cell       Date:  1990-12-21       Impact factor: 41.582

5.  Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene.

Authors:  H de Thé; M M Vivanco-Ruiz; P Tiollais; H Stunnenberg; A Dejean
Journal:  Nature       Date:  1990-01-11       Impact factor: 49.962

6.  Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinoic acid synthesis.

Authors:  G Duester; M L Shean; M S McBride; M J Stewart
Journal:  Mol Cell Biol       Date:  1991-03       Impact factor: 4.272

7.  A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter.

Authors:  W C Smith; H Nakshatri; P Leroy; J Rees; P Chambon
Journal:  EMBO J       Date:  1991-08       Impact factor: 11.598

8.  Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

Authors:  P Leroy; A Krust; A Zelent; C Mendelsohn; J M Garnier; P Kastner; A Dierich; P Chambon
Journal:  EMBO J       Date:  1991-01       Impact factor: 11.598

9.  Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

Authors:  A Zelent; C Mendelsohn; P Kastner; A Krust; J M Garnier; F Ruffenach; P Leroy; P Chambon
Journal:  EMBO J       Date:  1991-01       Impact factor: 11.598

10.  The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element.

Authors:  G Vasios; S Mader; J D Gold; M Leid; Y Lutz; M P Gaub; P Chambon; L Gudas
Journal:  EMBO J       Date:  1991-05       Impact factor: 11.598
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  52 in total

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Authors:  Behnom Farboud; Herborg Hauksdottir; Yun Wu; Martin L Privalsky
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

Review 2.  Mechanisms and significance of nuclear receptor auto- and cross-regulation.

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Journal:  Gen Comp Endocrinol       Date:  2010-03-23       Impact factor: 2.822

3.  Retinoic acid receptor alpha1 variants, RARalpha1DeltaB and RARalpha1DeltaBC, define a new class of nuclear receptor isoforms.

Authors:  A Parrado; G Despouy; R Kraïba; C Le Pogam; S Dupas; M Choquette; M Robledo; J Larghero; H Bui; I Le Gall; C Rochette-Egly; C Chomienne; R A Padua
Journal:  Nucleic Acids Res       Date:  2001-12-15       Impact factor: 16.971

4.  Ligand-dependent enhancement of human antithrombin gene expression by retinoid X receptor alpha and thyroid hormone receptor beta.

Authors:  R W Niessen; F Rezaee; P H Reitsma; M Peters; J J de Vijlder; A Sturk
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5.  Expression and regulation of nuclear retinoic acid receptors in human lymphoid cells.

Authors:  Mark Ballow; Xiaochuan Wang; Shunan Xiang; Cheryl Allen
Journal:  J Clin Immunol       Date:  2003-01       Impact factor: 8.317

6.  The chicken retinoid-X-receptor-gamma gene gives rise to two distinct species of mRNA with different patterns of expression.

Authors:  E A Seleiro; D Darling; P M Brickell
Journal:  Biochem J       Date:  1994-07-01       Impact factor: 3.857

Review 7.  How degrading: Cyp26s in hindbrain development.

Authors:  Richard J White; Thomas F Schilling
Journal:  Dev Dyn       Date:  2008-10       Impact factor: 3.780

8.  Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction.

Authors:  Guillermo Elizondo; Irma M Medina-Díaz; Raymundo Cruz; Frank J Gonzalez; Libia Vega
Journal:  Biochem Pharmacol       Date:  2008-10-17       Impact factor: 5.858

9.  Retinoic acid mediates long-paced oscillations in retinoid receptor activity: evidence for a potential role for RIP140.

Authors:  Kelly C Heim; Joshua J Gamsby; Mary P Hever; Sarah J Freemantle; Jennifer J Loros; Jay C Dunlap; Michael J Spinella
Journal:  PLoS One       Date:  2009-10-28       Impact factor: 3.240

10.  Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.

Authors:  Santhakumar Manicassamy; Rajesh Ravindran; Jiusheng Deng; Herold Oluoch; Timothy L Denning; Sudhir Pai Kasturi; Kristen M Rosenthal; Brian D Evavold; Bali Pulendran
Journal:  Nat Med       Date:  2009-03-01       Impact factor: 53.440
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