Literature DB >> 16586097

The ABCA subfamily--gene and protein structures, functions and associated hereditary diseases.

Christiane Albrecht1, Enrique Viturro.   

Abstract

To date, 12 members of the human ABCA subfamily are identified. They share a high degree of sequence conservation and have been mostly related with lipid trafficking in a wide range of body locations. Mutations in some of these genes have been described to cause severe hereditary diseases related with lipid transport, such as fatal surfactant deficiency or harlequin ichthyosis. In addition, most of them are hypothesized to participate in the subcellular sequestration of drugs, thereby being responsible for the resistance of several carcinoma cell lines against drug treatment. The objective of this review is to summarize the literature for this subfamily of ABC transporter proteins, excluding ABCA1 and ABCA4, which will be discussed in other chapters of this issue.

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Year:  2006        PMID： 16586097     DOI： 10.1007/s00424-006-0047-8

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  56 in total

1.  Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.

Authors:  K E Berge; H Tian; G A Graf; L Yu; N V Grishin; J Schultz; P Kwiterovich; B Shan; R Barnes; H H Hobbs
Journal:  Science       Date:  2000-12-01       Impact factor: 47.728

2.  Molecular structure of a novel cholesterol-responsive A subclass ABC transporter, ABCA9.

Authors:  Armin Piehler; Wolfgang E Kaminski; Jürgen J Wenzel; Thomas Langmann; Gerd Schmitz
Journal:  Biochem Biophys Res Commun       Date:  2002-07-12       Impact factor: 3.575

3.  Identification and characterization of a novel ABCA subfamily member, ABCA12, located in the lamellar ichthyosis region on 2q34.

Authors:  T Annilo; S Shulenin; Z Q Chen; I Arnould; C Prades; C Lemoine; C Maintoux-Larois; C Devaud; M Dean; P Denèfle; M Rosier
Journal:  Cytogenet Genome Res       Date:  2002       Impact factor: 1.636

4.  Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter.

Authors:  C Broccardo; J Osorio; M F Luciani; L M Schriml; C Prades; S Shulenin; I Arnould; L Naudin; C Lafargue; M Rosier; B Jordan; M G Mattei; M Dean; P Denèfle; G Chimini
Journal:  Cytogenet Cell Genet       Date:  2001

5.  Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein.

Authors:  N Klugbauer; F Hofmann
Journal:  FEBS Lett       Date:  1996-08-05       Impact factor: 4.124

6.  Subcellular localization of rat Abca5, a rat ATP-binding-cassette transporter expressed in Leydig cells, and characterization of its splice variant apparently encoding a half-transporter.

Authors:  Frauke Petry; Vera Ritz; Cornelia Meineke; Peter Middel; Thomas Kietzmann; Christoph Schmitz-Salue; Karen I Hirsch-Ernst
Journal:  Biochem J       Date:  2006-01-01       Impact factor: 3.857

7.  ABC transporter ABCA3 is expressed in acute myeloid leukemia blast cells and participates in vesicular transport.

Authors:  Gerald G Wulf; Simon Modlich; Nobuya Inagaki; Dirk Reinhardt; Roland Schroers; Frank Griesinger; Lorenz Trümper
Journal:  Haematologica       Date:  2004-11       Impact factor: 9.941

8.  Complete coding sequence, promoter region, and genomic structure of the human ABCA2 gene and evidence for sterol-dependent regulation in macrophages.

Authors:  W E Kaminski; A Piehler; K Püllmann; M Porsch-Ozcürümez; C Duong; G M Bared; C Büchler; G Schmitz
Journal:  Biochem Biophys Res Commun       Date:  2001-02-16       Impact factor: 3.575

9.  ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.

Authors:  Sandrine Macé; Emmanuelle Cousin; Sylvain Ricard; Emmanuelle Génin; Emmanuel Spanakis; Carole Lafargue-Soubigou; Bérengère Génin; Raphaël Fournel; Sandrine Roche; Gilles Haussy; Florence Massey; Stéphane Soubigou; Georges Bréfort; Patrick Benoit; Alexis Brice; Dominique Campion; Melvyn Hollis; Laurent Pradier; Jésus Benavides; Jean-François Deleuze
Journal:  Neurobiol Dis       Date:  2005-02       Impact factor: 5.996

10.  The human ATP binding cassette gene ABCA13, located on chromosome 7p12.3, encodes a 5058 amino acid protein with an extracellular domain encoded in part by a 4.8-kb conserved exon.

Authors:  C Prades; I Arnould; T Annilo; S Shulenin; Z Q Chen; L Orosco; M Triunfol; C Devaud; C Maintoux-Larois; C Lafargue; C Lemoine; P Denèfle; M Rosier; M Dean
Journal:  Cytogenet Genome Res       Date:  2002       Impact factor: 1.636
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  36 in total

1.  The extreme C terminus of the ABC protein DrrA contains unique motifs involved in function and assembly of the DrrAB complex.

Authors:  Han Zhang; Prajakta Pradhan; Parjit Kaur
Journal:  J Biol Chem       Date:  2010-09-27       Impact factor: 5.157

2.  A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments.

Authors:  Michael F Beers; Arie Hawkins; Henry Shuman; Ming Zhao; Jennifer L Newitt; Jean Ann Maguire; Wenge Ding; Surafel Mulugeta
Journal:  J Lipid Res       Date:  2011-05-17       Impact factor: 5.922

Review 3.  ATP-binding cassette transporter-2 (ABCA2) as a therapeutic target.

Authors:  Warren Davis; Kenneth D Tew
Journal:  Biochem Pharmacol       Date:  2017-12-06       Impact factor: 5.858

4.  Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa.

Authors:  Tinnakorn Chaiworapongsa; Roberto Romero; Amy Whitten; Adi L Tarca; Gaurav Bhatti; Sorin Draghici; Piya Chaemsaithong; Jezid Miranda; Sonia S Hassan
Journal:  J Perinat Med       Date:  2013-09-01       Impact factor: 1.901

Review 5.  ABCA1, from pathology to membrane function.

Authors:  Ana Zarubica; Doriane Trompier; Giovanna Chimini
Journal:  Pflugers Arch       Date:  2006-07-21       Impact factor: 3.657

6.  Expression, purification and structural properties of ABC transporter ABCA4 and its individual domains.

Authors:  Yaroslav Tsybovsky; Krzysztof Palczewski
Journal:  Protein Expr Purif       Date:  2014-02-28       Impact factor: 1.650

7.  Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells.

Authors:  Leilei Tang; Saskia M Bergevoet; Christian Gilissen; Theo de Witte; Joop H Jansen; Bert A van der Reijden; Reinier A P Raymakers
Journal:  BMC Pharmacol       Date:  2010-09-13

8.  A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.

Authors:  Helen M Knight; Benjamin S Pickard; Alan Maclean; Mary P Malloy; Dinesh C Soares; Allan F McRae; Alison Condie; Angela White; William Hawkins; Kevin McGhee; Margaret van Beck; Donald J MacIntyre; John M Starr; Ian J Deary; Peter M Visscher; David J Porteous; Ronald E Cannon; David St Clair; Walter J Muir; Douglas H R Blackwood
Journal:  Am J Hum Genet       Date:  2009-12       Impact factor: 11.025

Review 9.  Genetic disorders of surfactant dysfunction.

Authors:  Susan E Wert; Jeffrey A Whitsett; Lawrence M Nogee
Journal:  Pediatr Dev Pathol       Date:  2009 Jul-Aug

10.  Human ATP-binding cassette (ABC) transporter family.

Authors:  Vasilis Vasiliou; Konstandinos Vasiliou; Daniel W Nebert
Journal:  Hum Genomics       Date:  2009-04       Impact factor: 4.639
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