Literature DB >> 15531465

ABC transporter ABCA3 is expressed in acute myeloid leukemia blast cells and participates in vesicular transport.

Gerald G Wulf, Simon Modlich, Nobuya Inagaki, Dirk Reinhardt, Roland Schroers, Frank Griesinger, Lorenz Trümper.   

Abstract

Drug resistance is a major issue in the treatment of acute myeloid leukemia (AML), and drug efflux by ATP-binding-cassette (ABC) transporters is one of the main mechanism involved in this resistance. We determined the prevalence of the intracellular transporter ABCA3 in specimens from patients with AML, and addressed its biology with attention to intracellular compartmentalization.

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Year:  2004        PMID： 15531465

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


  6 in total

Review 1.  The ABCA subfamily--gene and protein structures, functions and associated hereditary diseases.

Authors:  Christiane Albrecht; Enrique Viturro
Journal:  Pflugers Arch       Date:  2006-04-04       Impact factor: 3.657

2.  ABC transporter A3 facilitates lysosomal sequestration of imatinib and modulates susceptibility of chronic myeloid leukemia cell lines to this drug.

Authors:  Bjoern Chapuy; Melanie Panse; Ulf Radunski; Raphael Koch; Dirk Wenzel; Nobuya Inagaki; Detlef Haase; Lorenz Truemper; Gerald G Wulf
Journal:  Haematologica       Date:  2009-11       Impact factor: 9.941

Review 3.  Leukemia and ABC transporters.

Authors:  Yu Fukuda; Shangli Lian; John D Schuetz
Journal:  Adv Cancer Res       Date:  2015-01-08       Impact factor: 5.767

4.  Genomic stability at the coding regions of the multidrug transporter gene ABCB1: insights into the development of alternative drug resistance mechanisms in human leukemia cells.

Authors:  Kevin G Chen; George E Duran; Mark J Mogul; Yan C Wang; Kevin L Ross; Jean-Pierre Jaffrézou; Lyn M Huff; Kory R Johnson; Tito Fojo; Norman J Lacayo; Branimir I Sikic
Journal:  Cancer Drug Resist       Date:  2020-11-03

5.  Prognostic impact of ABCA3 expression in adult and pediatric acute myeloid leukemia: an ALFA-ELAM02 joint study.

Authors:  Antony Ceraulo; Hélène Lapillonne; Meyling H Cheok; Claude Preudhomme; Hervé Dombret; Christine Terré; Juliette Lambert; Guy Leverger; Yves Bertrand; Franck Mortreux; Eric Wattel
Journal:  Blood Adv       Date:  2022-05-10

6.  The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia.

Authors:  Qi Shen; Sichu Liu; Junyan Hu; Shaohua Chen; Lijian Yang; Bo Li; Xiuli Wu; Yu Ma; Jianchang Yang; Yupo Ma; Yangqiu Li
Journal:  Cancer Cell Int       Date:  2012-10-15       Impact factor: 5.722
  6 in total

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