BACKGROUND: Our understanding of the biological basis for mucosal barrier injury (mucositis) induced by cancer therapy with radiation or drugs continues to evolve. A patient's mucosal response to cancer therapy appears to be controlled by both global (i.e. gender, underlying systemic disease, race) and tissue specific (i.e. epithelial type, intrinsic endocrine system, local microbial environment, function) factors. CONCLUSION: Interactions of these elements, coupled with underlying genetic influences, most likely govern the risk, course and severity of regimen-related mucosal injury.
BACKGROUND: Our understanding of the biological basis for mucosal barrier injury (mucositis) induced by cancer therapy with radiation or drugs continues to evolve. A patient's mucosal response to cancer therapy appears to be controlled by both global (i.e. gender, underlying systemic disease, race) and tissue specific (i.e. epithelial type, intrinsic endocrine system, local microbial environment, function) factors. CONCLUSION: Interactions of these elements, coupled with underlying genetic influences, most likely govern the risk, course and severity of regimen-related mucosal injury.
Authors: A David McCollum; Paul J Catalano; Daniel G Haller; Robert J Mayer; John S Macdonald; Al B Benson; Charles S Fuchs Journal: J Natl Cancer Inst Date: 2002-08-07 Impact factor: 13.506
Authors: Deborah B McGuire; Janet S Fulton; Jumin Park; Carlton G Brown; M Elvira P Correa; June Eilers; Sharon Elad; Faith Gibson; Loree K Oberle-Edwards; Joanne Bowen; Rajesh V Lalla Journal: Support Care Cancer Date: 2013-09-10 Impact factor: 3.603
Authors: J Bowen; N Al-Dasooqi; P Bossi; H Wardill; Y Van Sebille; A Al-Azri; E Bateman; M E Correa; J Raber-Durlacher; A Kandwal; B Mayo; R G Nair; A Stringer; K Ten Bohmer; D Thorpe; R V Lalla; S Sonis; K Cheng; S Elad Journal: Support Care Cancer Date: 2019-07-08 Impact factor: 3.603
Authors: Noor Al-Dasooqi; Stephen T Sonis; Joanne M Bowen; Emma Bateman; Nicole Blijlevens; Rachel J Gibson; Richard M Logan; Raj G Nair; Andrea M Stringer; Roger Yazbeck; Sharon Elad; Rajesh V Lalla Journal: Support Care Cancer Date: 2013-04-21 Impact factor: 3.603
Authors: Arsinoi Xanthinaki; Ourania Nicolatou-Galitis; Pavlina Athanassiadou; Maria Gonidi; Vassilis Kouloulias; Anastasia Sotiropoulou-Lontou; George Pissakas; Konstantinos Kyprianou; John Kouvaris; Efstratios Patsouris Journal: Support Care Cancer Date: 2008-01-16 Impact factor: 3.603
Authors: Noor Al-Dasooqi; Stephen T Sonis; Joanne M Bowen; Emma Bateman; Nicole Blijlevens; Rachel J Gibson; Richard M Logan; Raj G Nair; Andrea M Stringer; Roger Yazbeck; Sharon Elad; Rajesh V Lalla Journal: Support Care Cancer Date: 2013-07-11 Impact factor: 3.603