OBJECTIVE: To assess the absorption of magnesium (Mg) from mineral waters of different Mg content in comparison to low mineralized water and a Mg capsule. DESIGN: Randomized, controlled, double- blind trial in a crossover design with an additional control with a Mg capsule. SETTING: Institute of Balneology and Medical Climatology, Medical School of Hanover, Germany. SUBJECTS:22 healthy male volunteers aged between 23-46 years. INTERVENTION: After a standardized breakfast, each participant received, in Latin square order, 500 ml of either of two Mg-rich mineral waters (281 or 120 mg/l). As a control condition, a mineral water of low Mg content (8 mg/l) was used. A Mg capsule (Magnesium-Diasporal 150, Protina, Ismaning, Germany) was used for further comparisons. RESULTS:Changes in serum Mg levels in the first 4 hours after intake differed significantly between the groups (p = 0.030; ANOVA). Mean values differed between the Mg-rich mineral water conditions and the control conditions though did not reach statistical significance (p = 0.055), however, mean values did not differ between the test waters and the capsule (p = 0.338). CONCLUSION:Magnesium from mineral waters can easily be absorbed and its absorption rate is similar to that from a pharmaceutical Mg preparation.
RCT Entities:
OBJECTIVE: To assess the absorption of magnesium (Mg) from mineral waters of different Mg content in comparison to low mineralized water and a Mg capsule. DESIGN: Randomized, controlled, double- blind trial in a crossover design with an additional control with a Mg capsule. SETTING: Institute of Balneology and Medical Climatology, Medical School of Hanover, Germany. SUBJECTS: 22 healthy male volunteers aged between 23-46 years. INTERVENTION: After a standardized breakfast, each participant received, in Latin square order, 500 ml of either of two Mg-rich mineral waters (281 or 120 mg/l). As a control condition, a mineral water of low Mg content (8 mg/l) was used. A Mg capsule (Magnesium-Diasporal 150, Protina, Ismaning, Germany) was used for further comparisons. RESULTS: Changes in serum Mg levels in the first 4 hours after intake differed significantly between the groups (p = 0.030; ANOVA). Mean values differed between the Mg-rich mineral water conditions and the control conditions though did not reach statistical significance (p = 0.055), however, mean values did not differ between the test waters and the capsule (p = 0.338). CONCLUSION:Magnesium from mineral waters can easily be absorbed and its absorption rate is similar to that from a pharmaceutical Mg preparation.
Authors: Richard O Day; Winston Liauw; Lynette Mr Tozer; Patrick McElduff; Russell J Beckett; Kenneth M Williams Journal: BMC Res Notes Date: 2010-06-28
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