| Literature DB >> 16581376 |
Abstract
The energetic cost of partitioning peptide bonds into membrane bilayers is prohibitive unless the peptide bonds participate in hydrogen bonds. However, even then there is a significant free energy penalty for dehydrating the peptide bonds that can only be overcome by favorable hydrophobic interactions. Membrane protein structure formation is thus dominated by hydrogen bonding interactions, which is the subject of this review.Entities:
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Year: 2005 PMID： 16581376 DOI： 10.1016/S0065-3233(05)72006-4
Source DB: PubMed Journal: Adv Protein Chem ISSN： 0065-3233