| Literature DB >> 16580989 |
Emmanuelle Passegué1, Amy J Wagers.
Abstract
Blood-forming hematopoietic stem cells (HSCs) ensure production of all mature blood cells during homeostatic and regenerative hematopoiesis. Proliferation, cell cycle regulation, and quiescence are key processes involved in this function, and in a recent issue of Cancer Cell, show that HSC quiescence is actively regulated by specific molecular mechanisms that appear to distinguish normal HSC maintenance from HSC responses to hematologic injury.Entities:
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Year: 2006 PMID： 16580989 DOI： 10.1016/j.devcel.2006.03.002
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270