| Literature DB >> 16580987 |
Abstract
Although the activation of Smad signaling pathways downstream of TGF-beta superfamily ligands by receptor-mediated Smad phosphorylation is well understood, nothing is known about Smad phosphatases that turn off Smad activity. Recently in Genes & Development, describe pyruvate dehydrogenase phosphatase as a Smad1 phosphatase that functions in Drosophila in the Decapentaplegic pathway and in mammalian cells in the BMP pathway.Entities:
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Year: 2006 PMID： 16580987 DOI： 10.1016/j.devcel.2006.03.008
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270