BACKGROUND AND PURPOSE: The purpose of this study was to determine whether subjects with asymptomatic carotid artery stenosis and occlusion demonstrate deficits in physical performance compared with a comparison group. These deficits may indicate that a person is demonstrating preclinical disability. SUBJECTS: Seventy-one subjects with no known disease and 39 subjects with asymptomatic carotid artery stenosis of moderate and severe degrees or with occlusion were included. METHODS: Physical performance was assessed with the 9-item and 7-item versions of the Physical Performance Test (PPT). Individual tasks also were timed for the subjects with disease. RESULTS: There were significant differences between the comparison group and the subjects with carotid artery stenosis on the 9-item PPT (P<.00) and on the 7-item PPT (P<.03). Subjects with asymptomatic carotid artery stenosis and occlusion demonstrated less than optimal performance on the PPT (9-item PPT, mean=27 of 36; 7-item PPT, mean=21 of 28). Subjects with moderate stenosis were the slowest in performing the task of simulated eating. DISCUSSION AND CONCLUSION: Subjects with asymptomatic carotid artery stenosis and occlusion exhibited changes in function, as indicated by their performance on the PPT relative to that of a comparison group. This finding may be indicative of preclinical disability, indicating that these people are symptomatic. This indication may affect the medical and surgical options that can be considered for their care.
BACKGROUND AND PURPOSE: The purpose of this study was to determine whether subjects with asymptomatic carotid artery stenosis and occlusion demonstrate deficits in physical performance compared with a comparison group. These deficits may indicate that a person is demonstrating preclinical disability. SUBJECTS: Seventy-one subjects with no known disease and 39 subjects with asymptomatic carotid artery stenosis of moderate and severe degrees or with occlusion were included. METHODS: Physical performance was assessed with the 9-item and 7-item versions of the Physical Performance Test (PPT). Individual tasks also were timed for the subjects with disease. RESULTS: There were significant differences between the comparison group and the subjects with carotid artery stenosis on the 9-item PPT (P<.00) and on the 7-item PPT (P<.03). Subjects with asymptomatic carotid artery stenosis and occlusion demonstrated less than optimal performance on the PPT (9-item PPT, mean=27 of 36; 7-item PPT, mean=21 of 28). Subjects with moderate stenosis were the slowest in performing the task of simulated eating. DISCUSSION AND CONCLUSION: Subjects with asymptomatic carotid artery stenosis and occlusion exhibited changes in function, as indicated by their performance on the PPT relative to that of a comparison group. This finding may be indicative of preclinical disability, indicating that these people are symptomatic. This indication may affect the medical and surgical options that can be considered for their care.
Authors: Maha T Mohammad; Susan L Whitney; Patrick J Sparto; J Richard Jennings; Joseph M Furman Journal: J Neurol Phys Ther Date: 2010-06 Impact factor: 3.649
Authors: Vicki L Gray; Andrew P Goldberg; Mark W Rogers; Laila Anthony; Michael L Terrin; Jack M Guralnik; William C Blackwelder; Diana F H Lam; Siddhartha Sikdar; Brajesh K Lal Journal: J Vasc Surg Date: 2019-11-04 Impact factor: 4.268