Literature DB >> 16579607

Nucleic acid-functionalized Pt nanoparticles: Catalytic labels for the amplified electrochemical detection of biomolecules.

Ronen Polsky1, Ron Gill, Lubov Kaganovsky, Itamar Willner.   

Abstract

Nucleic acid-functionalized Pt nanoparticles (Pt-NPs) act as catalytic labels for the amplified electrochemical detection of DNA hybridization and aptamer/protein recognition. Hybridization of the nucleic acid-modified Pt-NPs with a sensing nucleic acid/analyte DNA complex associated with an electrode enables the amperometric, amplified, detection of the DNA by the Pt NP electrocatalyzed reduction of H2O2 (sensitivity limit, 1 x 10(-11) M). Similarly, the association of aptamer-functionalized Pt- NPs to a thrombin aptamer/thrombin complex associated with an electrode allowed the amplified, electrocatalytic detection of thrombin with a sensitivity limit corresponding to 1 x 10(-9) M.

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Year:  2006        PMID： 16579607     DOI： 10.1021/ac0519864

Source DB:  PubMed          Journal:  Anal Chem        ISSN： 0003-2700            Impact factor:   6.986


  29 in total

Review 1.  Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates.

Authors:  Jung Heon Lee; Mehmet V Yigit; Debapriya Mazumdar; Yi Lu
Journal:  Adv Drug Deliv Rev       Date:  2010-03-22       Impact factor: 15.470

Review 2.  Functional nucleic acid sensors.

Authors:  Juewen Liu; Zehui Cao; Yi Lu
Journal:  Chem Rev       Date:  2009-05       Impact factor: 60.622

3.  Colorimetric bio-barcode immunoassay for parathion based on amplification by using platinum nanoparticles acting as a nanozyme.

Authors:  Ge Chen; Maojun Jin; Mengmeng Yan; Xueyan Cui; Yuanshang Wang; Weijia Zheng; Guoxin Qin; Yudan Zhang; Mingjie Li; Yun Liao; Xiuyuan Zhang; Feiyan Yan; A M Abd El-Aty; Ahmet Hacımüftüoğlu; Jing Wang
Journal:  Mikrochim Acta       Date:  2019-05-09       Impact factor: 5.833

4.  Rapid colorimetric determination of the pesticides carbofuran and dichlorvos by exploiting their inhibitory effect on the aggregation of peroxidase-mimicking platinum nanoparticles.

Authors:  Jing Cao; Miao Wang; Yongxin She; A M Abd El-Aty; Ahmet Hacımüftüoğlu; Jing Wang; Mengmeng Yan; Sihui Hong; Shuibing Lao; Yanli Wang
Journal:  Mikrochim Acta       Date:  2019-05-31       Impact factor: 5.833

5.  Universal Biotin-PEG-Linked Gold Nanoparticle Probes for the Simultaneous Detection of Nucleic Acids and Proteins.

Authors:  Alexander W Scott; Viswanadham Garimella; Colin M Calabrese; Chad A Mirkin
Journal:  Bioconjug Chem       Date:  2016-10-14       Impact factor: 4.774

6.  Peptide-functionalized spherical polyelectrolyte nanobrushes for real-time sensing of protease activity.

Authors:  Bin-Cheng Yin; Min Zhang; Weihong Tan; Bang-Ce Ye
Journal:  Chembiochem       Date:  2010-03-01       Impact factor: 3.164

7.  Integration of platinum nanoparticles with a volumetric bar-chart chip for biomarker assays.

Authors:  Yujun Song; Xuefeng Xia; Xifeng Wu; Ping Wang; Lidong Qin
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-17       Impact factor: 15.336

8.  Sensitive immunosensor for cancer biomarker based on dual signal amplification strategy of graphene sheets and multienzyme functionalized carbon nanospheres.

Authors:  Dan Du; Zhexiang Zou; Yongsoon Shin; Jun Wang; Hong Wu; Mark H Engelhard; Jun Liu; Ilhan A Aksay; Yuehe Lin
Journal:  Anal Chem       Date:  2010-04-01       Impact factor: 6.986

9.  Electrochemical competitive immunodetection of messenger RNA modified with N6-methyladenosine by using DNA-modified mesoporous PtCo nanospheres.

Authors:  Xinying Ou; Qinli Pu; Shangchun Sheng; Tao Dai; Dan Gou; Wen Yu; Tingyan Yang; Ling Dai; Yujun Yang; Guoming Xie
Journal:  Mikrochim Acta       Date:  2019-12-09       Impact factor: 5.833

10.  Effects of TAT-conjugated platinum nanoparticles on lifespan of mitochondrial electron transport complex I-deficient Caenorhabditis elegans, nuo-1.

Authors:  Yuri Sakaue; Juewon Kim; Yusei Miyamoto
Journal:  Int J Nanomedicine       Date:  2010-09-20
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