Literature DB >> 16572563

Efficacy of surgical decompression in regard to motor recovery in the setting of conus medullaris injury.

Vafa Rahimi-Movaghar1, Alexander R Vaccaro, Mehdi Mohammadi.   

Abstract

BACKGROUND/
OBJECTIVE: An assessment of neurological improvement after surgical intervention in the setting of traumatic conus medullaris injury (CMI).
METHODS: A retrospective evaluation of a cohort of patients with a blunt traumatic CMI from T12 to L1. The neurologic and functional outcomes were recorded from the acute hospital admission to the most recent follow-up. Data collected included age, level of injury, neurologic examination according to the Frankel grading system and motor index score, and the mechanism and timing of CMI decompression.
RESULTS: A total of 24 patients with a mean age of 27 years (men, 87%) were identified. The most common level of bony injury was L1, and the most frequent mechanism of injury was a motor vehicle crash. Before surgical intervention, 16 of 24 patients (66.7%) had a complete neurological deficit below the level of injury. The median interval from injury to surgery was 6 days (range, 7 hours to 390 days). Decompression, fusion, and adjunctive internal fixation were the most common surgical procedures. Median length of follow-up was 32 months after surgery. Improvement in spinal cord and bladder function was seen in 41.6% and 63.6% of patients, respectively. Root recovery was seen in 83.3% of patients.
CONCLUSIONS: In the setting of CMI, no correlation between the timing of surgical decompression and motor improvement was identified. Root recovery was more predictable than spinal cord and bladder recovery.

Entities:  

Mesh:

Year:  2006        PMID: 16572563      PMCID: PMC1864791          DOI: 10.1080/10790268.2006.11753854

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  48 in total

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  11 in total

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Authors:  M Reinhold; C Knop; R Beisse; L Audigé; F Kandziora; A Pizanis; R Pranzl; E Gercek; M Schultheiss; A Weckbach; V Bühren; M Blauth
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4.  Prevalence of spinal cord injury in Tehran, Iran.

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5.  Spinal cord decompression: Is country of surgery a predictor of outcome?

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6.  Early versus late surgical decompression for traumatic thoracic/thoracolumbar (T1-L1) spinal cord injured patients. Primary results of a randomized controlled trial at one year follow-up.

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Review 7.  Mechanisms of spinal cord injury regeneration in zebrafish: a systematic review.

Authors:  Zeynab Noorimotlagh; Mahla Babaie; Mahdi Safdarian; Tahereh Ghadiri; Vafa Rahimi-Movaghar
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8.  The efficacy of surgical decompression before 24 hours versus 24 to 72 hours in patients with spinal cord injury from T1 to L1--with specific consideration on ethics: a randomized controlled trial.

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10.  Using recombinant Rho protein antagonist in acute spinal cord injury; does this go further from conventional decompressions?

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Journal:  Front Neurol       Date:  2013-02-05       Impact factor: 4.003

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