Literature DB >> 16557889

Pilot-scale production of group a and group C meningococcal polysaccharide immunogens.

S Berman1, P L Altieri, A Groffinger, J P Lowenthal.   

Abstract

Methods have been developed for the pilot-scale production of group A and group C meningococcal polysaccharide immunogens based on the meningococcal strains, the medium, and the basic processing procedures used by Gotschlich et al. Physical and chemical assays on the final products obtained on a pilot-scale level indicate that these purified polysaccharides are entirely comparable to the Gotschlich preparations which proved to be immunogenic in man.

Entities:  

Year:  1970        PMID： 16557889      PMCID： PMC416062          DOI： 10.1128/iai.2.5.640-643.1970

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  8 in total

1.  The specific hapten of group C (group II alpha) meningococcus. I. Preparation and immunological behavior.

Authors:  R G WATSON; H W SCHERP
Journal:  J Immunol       Date:  1958-10       Impact factor: 5.422

2.  Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method.

Authors:  L SVENNERHOLM
Journal:  Biochim Biophys Acta       Date:  1957-06

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Prevention of meningococcal disease by group C polysaccharide vaccine.

Authors:  M S Artenstein; R Gold; J G Zimmerly; F A Wyle; H Schneider; C Harkins
Journal:  N Engl J Med       Date:  1970-02-19       Impact factor: 91.245

5.  Simplified method for the production of carbohydrate antigen from Neisseria meningitidis.

Authors:  E Weiss; J L Long
Journal:  Appl Microbiol       Date:  1969-11

6.  Isolation and Characterization of Neisseria meningitidis Groups A, C, X, and Y Polysaccharide Antigens.

Authors:  J A Robinson; M A Apicella
Journal:  Infect Immun       Date:  1970-01       Impact factor: 3.441

7.  Human immunity to the meningococcus. IV. Immunogenicity of group A and group C meningococcal polysaccharides in human volunteers.

Authors:  E C Gotschlich; I Goldschneider; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307

8.  Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides.

Authors:  E C Gotschlich; T Y Liu; M S Artenstein
Journal:  J Exp Med       Date:  1969-06-01       Impact factor: 14.307
  8 in total
  3 in total

1.  Complex of meningococcal group B polysaccharide and type 2 outer membrane protein immunogenic in man.

Authors:  W D Zollinger; R E Mandrell; J M Griffiss; P Altieri; S Berman
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

2.  Immunological cross-reaction between a naturally occurring galactan, agarose, and an LPS locus for immune lysis of Neisseria meningitidis by human sera.

Authors:  J M Griffiss; D K Goroff
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330

3.  Antibody responses to meningococcal polysaccharide vaccines.

Authors:  B L Brandt; M S Artenstein; C D Smith
Journal:  Infect Immun       Date:  1973-10       Impact factor: 3.441
  3 in total

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