Literature DB >> 16557792

Effect of formalin treatment on electrophoretic mobility of cholera toxin.

V M Esposito1, J C Feeley.   

Abstract

Crude cholera toxin detoxified by treatment with Formalin showed an increased mobility and a decrease in the number of detectable protein constituents when compared with the parent toxin by disc electrophoresis. The significance of these observations in relation to the enhanced antigenic activity of cholera toxoid as compared to parent toxin is discussed.

Entities:  

Year:  1970        PMID： 16557792      PMCID： PMC415976          DOI： 10.1128/iai.2.1.120-122.1970

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  5 in total

1.  DISC ELECTROPHORESIS. I. BACKGROUND AND THEORY.

Authors:  L ORNSTEIN
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  A permeability factor (toxin) found in cholera stools and culture filtrates and its neutralization by convalescent cholera sera.

Authors:  J P Craig
Journal:  Nature       Date:  1965-08-07       Impact factor: 49.962

3.  Tetanus toxin and antigenic derivatives. II. Effect of protein and formaldehyde concentration on toxoid formation.

Authors:  S G Murphy
Journal:  J Bacteriol       Date:  1967-09       Impact factor: 3.490

4.  Cholera toxins: purification and preliminary characterization of ileal loop reactive type 2 toxin.

Authors:  W H Coleman; J Kaur; M E Iwert; G J Kasai; W Burrows
Journal:  J Bacteriol       Date:  1968-10       Impact factor: 3.490

5.  Pathogenesis of experimental cholera. Preparation and isolation of choleragen and choleragenoid.

Authors:  R A Finkelstein; J J LoSpalluto
Journal:  J Exp Med       Date:  1969-07-01       Impact factor: 14.307
  5 in total

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