| Literature DB >> 16550292 |
Anila I Khan1, T H Samuel Tan, Jason Micklefield.
Abstract
The introduction of (7'S)-methyl groups into the backbone of pyrrolidine-amide oligonucleotide mimics (POM) does not interfere with high affinity recognition of complementary nucleic acids, whereas (7'R)-methylation disrupts hybridisation significantly.Entities:
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Year: 2006 PMID： 16550292 DOI： 10.1039/b518171b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222