Literature DB >> 16535114

Selection and Characterization of Aspartokinase Feedback-Insensitive Mutants of Azotobacter vinelandii.

C R Ekechukwu, T A Burns, T Melton.   

Abstract

Aspartokinase feedback-insensitive mutants of Azotobacter vinelandii were selected as resistant to l-threonine, (beta)-hydroxynorvaline, or S-(2-aminoethyl)-l-cysteine. l-Threonine-resistant strains were classified into three groups based on their ability to transport l-threonine and their growth response to O-methylthreonine and (beta)-hydroxynorvaline. Most of the mutants were transport defective; however, some were desensitized to feedback regulation.

Entities:  

Year:  1995        PMID： 16535114      PMCID： PMC1388568          DOI： 10.1128/aem.61.8.3189-3191.1995

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  19 in total

1.  CONTROL OF ENZYME ACTIVITY BY CONCERTED FEEDBACK INHIBITION.

Authors:  P DATTA; H GEST
Journal:  Proc Natl Acad Sci U S A       Date:  1964-10       Impact factor: 11.205

2.  [Effect of amino acids on the beta-aspartokinase activity from Corynebacterium glutamicum of wild and mutant strains].

Authors:  S N Kara-murza; L V Ivanovskaia; N I Zhdanova
Journal:  Prikl Biokhim Mikrobiol       Date:  1978 May-Jun

3.  Formation of the nitrogen-fixing enzyme system in Azotobacter vinelandii.

Authors:  G W Strandberg; P W Wilson
Journal:  Can J Microbiol       Date:  1968-01       Impact factor: 2.419

4.  The aspartate kinase of Pseudomonas putida. Regulation of synthesis and activity.

Authors:  M Robert-Gero; M Poiret; G N Cohen
Journal:  Biochim Biophys Acta       Date:  1970-04-22

5.  The regulation of aspartokinase in Bacillus licheniformis.

Authors:  B H Gray; R W Bernlohr
Journal:  Biochim Biophys Acta       Date:  1969-04-22

6.  Concerted inhibition and its reversal by end products of aspartate kinase in Brevibacterium flavum.

Authors:  I Shiio; R Miyajima
Journal:  J Biochem       Date:  1969-06       Impact factor: 3.387

7.  Nucleotide sequence of the metL gene of Escherichia coli. Its product, the bifunctional aspartokinase ii-homoserine dehydrogenase II, and the bifunctional product of the thrA gene, aspartokinase I-homoserine dehydrogenase I, derive from a common ancestor.

Authors:  M M Zakin; N Duchange; P Ferrara; G N Cohen
Journal:  J Biol Chem       Date:  1983-03-10       Impact factor: 5.157

8.  Isolation and characterization of ack and pta mutations in Azotobacter vinelandii affecting acetate-glucose diauxie.

Authors:  D McKenney; T Melton
Journal:  J Bacteriol       Date:  1986-01       Impact factor: 3.490

9.  Evidence for a methionine-controlled homoserine dehydrogenase in Salmonella typhimurium.

Authors:  R L Cafferata; M Freundlich
Journal:  J Bacteriol       Date:  1969-01       Impact factor: 3.490

10.  Nucleotide sequence of the promoter region of the E. coli lysC gene.

Authors:  M Cassan; J Ronceray; J C Patte
Journal:  Nucleic Acids Res       Date:  1983-09-24       Impact factor: 16.971
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  1 in total

Review 1.  Cohesion group approach for evolutionary analysis of aspartokinase, an enzyme that feeds a branched network of many biochemical pathways.

Authors:  Chien-Chi Lo; Carol A Bonner; Gary Xie; Mark D'Souza; Roy A Jensen
Journal:  Microbiol Mol Biol Rev       Date:  2009-12       Impact factor: 11.056
  1 in total

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