Literature DB >> 16529135

Fate of bicuspid aortic valves in patients undergoing aortic root repair or replacement for aortic root enlargement.

Gruschen R Veldtman1, Heidi M Connolly, Thomas A Orszulak, Joseph A Dearani, Hartzell V Schaff.   

Abstract

OBJECTIVE: To better understand the outcome of the bicuspid aortic valve (BAV) after valve-sparing root replacement, we evaluated BAV function after its preservation at the time of the ascending aorta (AA) repair. PATIENTS AND METHODS: From January 1, 1994, through March 31, 2002, BAVs were preserved during repair of AA aneurysms in 21 patients (mean +/- SD age, 45+/-12 years; 13 males). We reviewed the clinical and surgical records of these patients for baseline characteristics, operative procedures, and data at latest follow-up.
RESULTS: The primary indication for operation was AA enlargement (median diameter, 55 mm; range, 43-65 mm) in 18 patients and severe aortic regurgitation (AR) in 3 patients. Preoperatively, the BAV exhibited mild or moderate stenosis in 5 patients (mean gradient, 25 mm Hg; range, 19-34 mm Hg), moderate AR in 2, and severe AR in 3. Aortic valve repair was performed in 11 patients. Seventeen patients had excision and graft replacement of the enlarged AA, and 4 patients had primary AA repair. There were no perioperative deaths. Moderate or severe AR was relieved in all patients early postoperatively and during follow-up (median, 2.5 years; maximum, 7.6 years). One patient required aortic valve replacement at 4.8 years for AR. An additional patient had recurrent, severe AR but was asymptomatic and has not undergone reoperation.
CONCLUSION: Repair of diseased BAVs or preservation of functionally normal BAVs during surgery for AA aneurysms has a low perioperative risk, and early results are encouraging. Additional observation is necessary to determine whether this strategy has real advantages over early aortic valve replacement.

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Year:  2006        PMID: 16529135     DOI: 10.4065/81.3.322

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  4 in total

1.  Bicuspid aortic root spared during ascending aorta surgery: an update of long-term results.

Authors:  Marco Russo; Guglielmo Saitto; Paolo Nardi; Fabio Bertoldo; Carlo Bassano; Antonio Scafuri; Antonio Pellegrino; Giovanni Ruvolo
Journal:  J Thorac Dis       Date:  2017-06       Impact factor: 2.895

Review 2.  Thoracic aortic aneurysm: unlocking the "silent killer" secrets.

Authors:  Ayman A Saeyeldin; Camilo A Velasquez; Syed Usman B Mahmood; Adam J Brownstein; Mohammad A Zafar; Bulat A Ziganshin; John A Elefteriades
Journal:  Gen Thorac Cardiovasc Surg       Date:  2017-12-04

3.  Geometric orientation of the aortic neoroot in patients with raphed bicuspid aortic valve disease undergoing primary cusp repair and a root reimplantation procedure.

Authors:  Prashanth Vallabhajosyula; Wilson Y Szeto; Caroline M Komlo; Liam P Ryan; Tyler J Wallen; Robert C Gorman; Nimesh D Desai; Joseph E Bavaria
Journal:  Eur J Cardiothorac Surg       Date:  2013-07-05       Impact factor: 4.191

4.  Commentary: Managing Thoracic Aortic Aneurysm in Patients with Bicuspid Aortic Valve Based on Aortic Root-Involvement.

Authors:  Marco Russo; Paolo Nardi; Guglielmo Saitto; Fabio Bertoldo; Giovanni Ruvolo
Journal:  Front Physiol       Date:  2017-10-30       Impact factor: 4.566

  4 in total

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