Literature DB >> 16523720

[Biological activity and pharmacological prospects of lupane terpenoids: I. Natural lupane derivatives].

T G Tolstikova, I V Sorokina, G A Tolstikov, A G Tolstikov, O B Flekhter.   

Abstract

The biological activity of natural and semisynthetic lupane triterpenoids is discussed in a two-part review. The first part is devoted to the pharmacological properties of natural lupane triterpenoids. Betulinic acid has proven to be the most effective antitumor agent among more than fifty natural lupanes.

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Year:  2006        PMID： 16523720     DOI： 10.1134/s1068162006010031

Source DB:  PubMed          Journal:  Bioorg Khim        ISSN： 0132-3423


  13 in total

1.  Triterpenoid resinous metabolites from the genus Boswellia: pharmacological activities and potential species-identifying properties.

Authors:  Yuxin Zhang; Zhangchi Ning; Cheng Lu; Siyu Zhao; Jianfen Wang; Baoqin Liu; Xuegong Xu; Yuanyan Liu
Journal:  Chem Cent J       Date:  2013-09-12       Impact factor: 4.215

2.  Identification and isolation of pharmacologically active triterpenes in Betuale cortex, Betula pendula Roth., Betulaceae.

Authors:  Elvira E Kovac-Besović; Kemal Durić; Zdenka Kalodera; Emin Sofić
Journal:  Bosn J Basic Med Sci       Date:  2009-02       Impact factor: 3.363

3.  Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B.

Authors:  Tiantian Jin; Haibo Yu; Xu-Feng Huang
Journal:  Sci Rep       Date:  2016-02-11       Impact factor: 4.379

4.  Screening of filamentous fungi to identify biocatalysts for lupeol biotransformation.

Authors:  Tatiane C de Carvalho; Aline M Polizeli; Izabel C C Turatti; Marcela E Severiano; Carlos E de Carvalho; Sérgio R Ambrósio; Antônio E M Crotti; Uir S de Figueiredo; Paulo C Vieira; Niege A J C Furtado
Journal:  Molecules       Date:  2010-09-01       Impact factor: 4.411

5.  Catalytic Sulfation of Betulin with Sulfamic Acid: Experiment and DFT Calculation.

Authors:  Aleksandr S Kazachenko; Feride Akman; Natalya Yu Vasilieva; Noureddine Issaoui; Yuriy N Malyar; Aleksandr A Kondrasenko; Valentina S Borovkova; Angelina V Miroshnikova; Anna S Kazachenko; Omar Al-Dossary; Marek J Wojcik; Yaroslava D Berezhnaya; Evgeniy V Elsuf'ev
Journal:  Int J Mol Sci       Date:  2022-01-29       Impact factor: 5.923

6.  Evaluation of A-azepano-triterpenoids and related derivatives as antimicrobial and antiviral agents.

Authors:  Oxana Kazakova; Elena Tret'yakova; Dmitry Baev
Journal:  J Antibiot (Tokyo)       Date:  2021-07-12       Impact factor: 2.649

7.  Study of the betulin enriched birch bark extracts effects on human carcinoma cells and ear inflammation.

Authors:  Cristina A Dehelean; Codruţa Soica; Ionuţ Ledeţi; Mihaela Aluaş; Istvan Zupko; Atena G Luşcan; Simona Cinta-Pinzaru; Melania Munteanu
Journal:  Chem Cent J       Date:  2012-11-19       Impact factor: 4.215

8.  Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells.

Authors:  Sen Wang; Kexin Wang; Chundong Zhang; Wanfeng Zhang; Qian Xu; Yitao Wang; Yulin Zhang; Yi Li; Ying Zhang; Huifang Zhu; Fangzhou Song; Yunlong Lei; Youquan Bu
Journal:  Cell Death Dis       Date:  2017-10-05       Impact factor: 8.469

9.  A practical synthesis of betulonic acid using selective oxidation of betulin on aluminium solid support.

Authors:  Nina Melnikova; Irina Burlova; Tatiana Kiseleva; Irina Klabukova; Marina Gulenova; Capital A Cyrillicleksey Kislitsin; Viktor Vasin; Boris Tanaseichuk
Journal:  Molecules       Date:  2012-10-09       Impact factor: 4.411

10.  Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents.

Authors:  Tatyana S Khlebnicova; Yuri A Piven; Fedor A Lakhvich; Iryna V Sorokina; Tatiana S Frolova; Dmitry S Baev; Tatyana G Tolstikova
Journal:  Antiinflamm Antiallergy Agents Med Chem       Date:  2020
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