Literature DB >> 16522150

Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54.

Sandra Coecke1, Hans Ahr, Bas J Blaauboer, Susanne Bremer, Silvia Casati, Josè Castell, Robert Combes, Raffaella Corvi, Charles L Crespi, Michael L Cunningham, Greetje Elaut, Brighitta Eletti, Andreas Freidig, Alessandra Gennari, Jean-François Ghersi-Egea, Andre Guillouzo, Thomas Hartung, Peter Hoet, Magnus Ingelman-Sundberg, Sharon Munn, Walter Janssens, Bernhard Ladstetter, David Leahy, Anthony Long, Annarita Meneguz, Mario Monshouwer, Siegfried Morath, Fred Nagelkerke, Olavi Pelkonen, Jessica Ponti, Pilar Prieto, Lysianne Richert, Enrico Sabbioni, Beatrice Schaack, Winfried Steiling, Emanuela Testai, Joan-Albert Vericat, Andrew Worth.   

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Year:  2006        PMID： 16522150     DOI： 10.1177/026119290603400113

Source DB:  PubMed          Journal:  Altern Lab Anim        ISSN： 0261-1929            Impact factor:   1.303


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  25 in total

1.  Comparison of toxicogenomic responses to phthalate ester exposure in an organotypic testis co-culture model and responses observed in vivo.

Authors:  Sean Harris; Sanne A B Hermsen; Xiaozhong Yu; Sung Woo Hong; Elaine M Faustman
Journal:  Reprod Toxicol       Date:  2015-10-22       Impact factor: 3.143

2.  Molecular effects of fractional ablative erbium:YAG laser treatment with multiple stacked pulses on standardized human three-dimensional organotypic skin models.

Authors:  Laurenz Schmitt; P M Amann; Y Marquardt; R Heise; K Czaja; P A Gerber; T Steiner; F Hölzle; Jens Malte Baron
Journal:  Lasers Med Sci       Date:  2017-03-15       Impact factor: 3.161

Review 3.  Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.

Authors:  Jon Hamm; Kristie Sullivan; Amy J Clippinger; Judy Strickland; Shannon Bell; Barun Bhhatarai; Bas Blaauboer; Warren Casey; David Dorman; Anna Forsby; Natàlia Garcia-Reyero; Sean Gehen; Rabea Graepel; Jon Hotchkiss; Anna Lowit; Joanna Matheson; Elissa Reaves; Louis Scarano; Catherine Sprankle; Jay Tunkel; Dan Wilson; Menghang Xia; Hao Zhu; David Allen
Journal:  Toxicol In Vitro       Date:  2017-01-06       Impact factor: 3.500

4.  21st Century Cell Culture for 21st Century Toxicology.

Authors:  David Pamies; Thomas Hartung
Journal:  Chem Res Toxicol       Date:  2016-12-05       Impact factor: 3.739

5.  A Demonstration of the Uncertainty in Predicting the Estrogenic Activity of Individual Chemicals and Mixtures From an In Vitro Estrogen Receptor Transcriptional Activation Assay (T47D-KBluc) to the In Vivo Uterotrophic Assay Using Oral Exposure.

Authors:  Justin M Conley; Bethany R Hannas; Johnathan R Furr; Vickie S Wilson; L Earl Gray
Journal:  Toxicol Sci       Date:  2016-07-29       Impact factor: 4.849

6.  Toxicity testing in the 21st century: a vision and a strategy.

Authors:  Daniel Krewski; Daniel Acosta; Melvin Andersen; Henry Anderson; John C Bailar; Kim Boekelheide; Robert Brent; Gail Charnley; Vivian G Cheung; Sidney Green; Karl T Kelsey; Nancy I Kerkvliet; Abby A Li; Lawrence McCray; Otto Meyer; Reid D Patterson; William Pennie; Robert A Scala; Gina M Solomon; Martin Stephens; James Yager; Lauren Zeise
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2010-02       Impact factor: 6.393

7.  Phthalate metabolism and kinetics in an in vitro model of testis development.

Authors:  Sean Harris; Susanna Wegner; Sung Woo Hong; Elaine M Faustman
Journal:  Toxicol In Vitro       Date:  2015-12-10       Impact factor: 3.500

8.  In vitro screening for population variability in chemical toxicity.

Authors:  Shannon H O'Shea; John Schwarz; Oksana Kosyk; Pamela K Ross; Min Jin Ha; Fred A Wright; Ivan Rusyn
Journal:  Toxicol Sci       Date:  2010-10-15       Impact factor: 4.849

9.  Bovine liver slices combined with an androgen transcriptional activation assay: an in-vitro model to study the metabolism and bioactivity of steroids.

Authors:  S Wang; J C W Rijk; J H Riethoff-Poortman; S Van Kuijk; A A C M Peijnenburg; T F H Bovee
Journal:  Anal Bioanal Chem       Date:  2010-03-17       Impact factor: 4.142

Review 10.  Perspectives on In Vitro to In Vivo Extrapolations.

Authors:  Thomas Hartung
Journal:  Appl In Vitro Toxicol       Date:  2018-12-08
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