OBJECTIVE: To evaluate the relation between placental proximity and frequency of birth weight discordance and small-for-gestational age (SGA) infants. STUDY DESIGN: Retrospective three-tier chorionicity analysis of 1155 twin placentas comparing birth weight characteristics of the twins in different placental types. RESULTS: Dichorionic-separate, but not dichorionic-fused twins, are heavier than monochorionic-diamniotic and monoamniotic twins (2376+/-721 vs. 2274+/-770, P < 0.006, and 2376+/-721 vs. 2166+/-782, P < 0.04). SGA twins are less frequent among dichorionic twins (OR 0.4; 95% CI 0.3, 0.6). Fewer sets with two SGA infants are present among dichorionic-separate compared to monochorionic-diamniotic pairs (OR 0.3; 95% CI 0.1, 0.8). The same trends are found when comparing all dichorionic to all monochorionic twins. Twins of all placental types have similar gestational ages and discordance values. CONCLUSIONS: Dichorionic-separate placentas are least likely to experience 'placental crowding' and thus are associated with heavier twins and fewer sets with one or two SGA infants.
OBJECTIVE: To evaluate the relation between placental proximity and frequency of birth weight discordance and small-for-gestational age (SGA) infants. STUDY DESIGN: Retrospective three-tier chorionicity analysis of 1155 twin placentas comparing birth weight characteristics of the twins in different placental types. RESULTS: Dichorionic-separate, but not dichorionic-fused twins, are heavier than monochorionic-diamniotic and monoamniotic twins (2376+/-721 vs. 2274+/-770, P < 0.006, and 2376+/-721 vs. 2166+/-782, P < 0.04). SGA twins are less frequent among dichorionic twins (OR 0.4; 95% CI 0.3, 0.6). Fewer sets with two SGA infants are present among dichorionic-separate compared to monochorionic-diamniotic pairs (OR 0.3; 95% CI 0.1, 0.8). The same trends are found when comparing all dichorionic to all monochorionic twins. Twins of all placental types have similar gestational ages and discordance values. CONCLUSIONS: Dichorionic-separate placentas are least likely to experience 'placental crowding' and thus are associated with heavier twins and fewer sets with one or two SGA infants.
Authors: Niyati Mukherjee; Chaeryon Kang; Honor M Wolfe; Barbara S Hertzberg; J Keith Smith; Weili Lin; Guido Gerig; Robert M Hamer; John H Gilmore Journal: Early Hum Dev Date: 2008-09-19 Impact factor: 2.079
Authors: Alexa A Freedman; Carol J Hogue; Carmen J Marsit; Augustine Rajakumar; Alicia K Smith; Katherine L Grantz; Robert L Goldenberg; Donald J Dudley; George R Saade; Robert M Silver; Karen J Gibbins; Radek Bukowski; Carolyn Drews-Botsch Journal: Am J Epidemiol Date: 2019-03-01 Impact factor: 4.897
Authors: Linda Booij; Dongsha Wang; Mélissa L Lévesque; Richard E Tremblay; Moshe Szyf Journal: Philos Trans R Soc Lond B Biol Sci Date: 2013-02-25 Impact factor: 6.237