Literature DB >> 16517922

Usefulness of eschar PCR for diagnosis of scrub typhus.

Seung-Hyun Lee1, Dong-Min Kim, Young Shin Cho, Sung Ho Yoon, Soo Kyoung Shim.   

Abstract

We report here on the case of a child who was infected with scrub typhus, and we made the diagnosis according to the serology and by performing PCRs on the child's eschar. The patient was treated with azithromycin, and he did not experience any complications. Performing nested PCR on the eschar might be both a rapid diagnostic test for scrub typhus in the early acute stage and a differential test as to whether or not a scab is a scrub typhus eschar.

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Year:  2006        PMID: 16517922      PMCID: PMC1393074          DOI: 10.1128/JCM.44.3.1169-1171.2006

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  8 in total

1.  Serological diagnosis of scrub typhus by indirect immunofluorescence.

Authors:  F M BOZEMAN; B L ELISBERG
Journal:  Proc Soc Exp Biol Med       Date:  1963-03

2.  A comparative trial of a single dose of azithromycin versus doxycycline for the treatment of mild scrub typhus.

Authors:  Yeon-Sook Kim; Hwan-Jung Yun; Soo Kyoung Shim; Sun Hoe Koo; Sun Young Kim; Samyong Kim
Journal:  Clin Infect Dis       Date:  2004-10-11       Impact factor: 9.079

3.  Azithromycin therapy for scrub typhus during pregnancy.

Authors:  E K Choi; H Pai
Journal:  Clin Infect Dis       Date:  1998-12       Impact factor: 9.079

4.  Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand.

Authors:  G Watt; P Kantipong; K Jongsakul; P Watcharapichat; D Phulsuksombati
Journal:  Antimicrob Agents Chemother       Date:  1999-11       Impact factor: 5.191

5.  Antigenic diversity of rickettsia tsutsugamushi: epidemiologic and ecologic significance.

Authors:  B L Elisberg; J M Campbell; F M Bozeman
Journal:  J Hyg Epidemiol Microbiol Immunol       Date:  1968

6.  Central nervous system involvement in patients with scrub typhus.

Authors:  H Pai; S Sohn; Y Seong; S Kee; W H Chang; K W Choe
Journal:  Clin Infect Dis       Date:  1997-03       Impact factor: 9.079

7.  In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus.

Authors:  D Strickman; T Sheer; K Salata; J Hershey; G Dasch; D Kelly; R Kuschner
Journal:  Antimicrob Agents Chemother       Date:  1995-11       Impact factor: 5.191

8.  Serotype-specific amplification of Rickettsia tsutsugamushi DNA by nested polymerase chain reaction.

Authors:  Y Furuya; Y Yoshida; T Katayama; S Yamamoto; A Kawamura
Journal:  J Clin Microbiol       Date:  1993-06       Impact factor: 5.948

  8 in total
  15 in total

1.  Scrub typhus: audit of an outbreak.

Authors:  Mani Ram Krishna; B Vasuki; K Nagaraju
Journal:  Indian J Pediatr       Date:  2015-01-14       Impact factor: 1.967

2.  Controlled trial of a 5-day course of telithromycin versus doxycycline for treatment of mild to moderate scrub typhus.

Authors:  Dong-Min Kim; Ki Dong Yu; Ji Hyun Lee; Hyun Kuk Kim; Seung-Hyun Lee
Journal:  Antimicrob Agents Chemother       Date:  2007-04-02       Impact factor: 5.191

3.  Scrub Typhus: Seven-Year Experience and Literature Review.

Authors:  Hwee-Kheng Lim; Jinn-Ming Wang
Journal:  J Acute Med       Date:  2018-09-01

4.  Eschar- a forgotten focus of concern.

Authors:  S Senthilkumaran; N Balamurgan; V Karthikeyan; P Thirumalaikolundusubramanian
Journal:  J Glob Infect Dis       Date:  2010-05

5.  Scrub typhus hepatitis confirmed by immunohistochemical staining.

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Journal:  World J Gastroenterol       Date:  2012-09-28       Impact factor: 5.742

6.  Acute renal failure due to acute tubular necrosis caused by direct invasion of Orientia tsutsugamushi.

Authors:  Dong-Min Kim; Dae Woong Kang; Jong O Kim; Jong Hoon Chung; Hyun Lee Kim; Chi Young Park; Sung-Chul Lim
Journal:  J Clin Microbiol       Date:  2007-11-14       Impact factor: 5.948

7.  Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal.

Authors:  Oleg Mediannikov; Cristina Socolovschi; Matthieu Million; Cheikh Sokhna; Hubert Bassene; Georges Diatta; Florence Fenollar; Didier Raoult
Journal:  Am J Trop Med Hyg       Date:  2014-09-08       Impact factor: 2.345

8.  Bartonella henselae in skin biopsy specimens of patients with cat-scratch disease.

Authors:  Emmanouil Angelakis; Sophie Edouard; Bernard La Scola; Didier Raoult
Journal:  Emerg Infect Dis       Date:  2010-12       Impact factor: 6.883

9.  Identification of rickettsial infections by using cutaneous swab specimens and PCR.

Authors:  Yassina Bechah; Cristina Socolovschi; Didier Raoult
Journal:  Emerg Infect Dis       Date:  2011-01       Impact factor: 6.883

10.  Diagnosis of Queensland tick typhus and African tick bite fever by PCR of lesion swabs.

Authors:  Jin Mei Wang; Bernard J Hudson; Matthew R Watts; Tom Karagiannis; Noel J Fisher; Catherine Anderson; Paul Roffey
Journal:  Emerg Infect Dis       Date:  2009-06       Impact factor: 6.883

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