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Literature DB >> 10543774

Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand.

G Watt¹, P Kantipong, K Jongsakul, P Watcharapichat, D Phulsuksombati.

Abstract

Azithromycin was given to mice and humans infected with strains of Orientia tsutsugamushi from northern Thailand, where drug-resistant scrub typhus occurs. Azithromycin and doxycycline yielded comparable mouse survival rates (73 and 79%, respectively; P > 0.5). Symptoms, signs, and fever in two pregnant women abated rapidly with azithromycin. Prospective human trials are needed.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1999 PMID： 10543774 PMCID： PMC89570

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

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Journal: J Infect Dis Date: 1998-03 Impact factor: 5.226

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Journal: Clin Infect Dis Date: 1994-04 Impact factor: 9.079

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Authors: G Watt; C Chouriyagune; R Ruangweerayud; P Watcharapichat; D Phulsuksombati; K Jongsakul; P Teja-Isavadharm; D Bhodhidatta; K D Corcoran; G A Dasch; D Strickman
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10. In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus.

Authors: D Strickman; T Sheer; K Salata; J Hershey; G Dasch; D Kelly; R Kuschner
Journal: Antimicrob Agents Chemother Date: 1995-11 Impact factor: 5.191

17 in total

1. Controlled trial of a 5-day course of telithromycin versus doxycycline for treatment of mild to moderate scrub typhus.

Authors: Dong-Min Kim; Ki Dong Yu; Ji Hyun Lee; Hyun Kuk Kim; Seung-Hyun Lee
Journal: Antimicrob Agents Chemother Date: 2007-04-02 Impact factor: 5.191

Review 2. Gene expression and involvement of signaling pathways during host-pathogen interplay in Orientia tsutsugamushi infection.

Authors: Subhasmita Panda; Subrat Kumar Swain; Basanta Pravas Sahu; Rachita Sarangi
Journal: 3 Biotech Date: 2022-07-19 Impact factor: 2.893

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Authors: Rose McGready; Elizabeth A Ashley; Vanaporn Wuthiekanun; Saw Oo Tan; Mupawjay Pimanpanarak; Samuel Jacher Viladpai-Nguen; Wilarat Jesadapanpong; Stuart D Blacksell; Sharon J Peacock; Daniel H Paris; Nicholas P Day; Pratap Singhasivanon; Nicholas J White; François Nosten
Journal: PLoS Negl Trop Dis Date: 2010-11-16

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Authors: Seung-Hyun Lee; Dong-Min Kim; Young Shin Cho; Sung Ho Yoon; Soo Kyoung Shim
Journal: J Clin Microbiol Date: 2006-03 Impact factor: 5.948

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Authors: Fabián E Díaz; Katia Abarca; Alexis M Kalergis
Journal: Clin Microbiol Rev Date: 2018-01-31 Impact factor: 26.132

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Authors: Kriangsak Phimda; Siriwan Hoontrakul; Chuanpit Suttinont; Sompong Chareonwat; Kitti Losuwanaluk; Sunee Chueasuwanchai; Wirongrong Chierakul; Duangjai Suwancharoen; Saowaluk Silpasakorn; Watcharee Saisongkorh; Sharon J Peacock; Nicholas P J Day; Yupin Suputtamongkol
Journal: Antimicrob Agents Chemother Date: 2007-07-16 Impact factor: 5.191

7. Pregnancy outcome in relation to treatment of murine typhus and scrub typhus infection: a fever cohort and a case series analysis.

Authors: Rose McGready; John Antony Jude Prakash; Santosh Joseph Benjamin; Wanitda Watthanaworawit; Tippawan Anantatat; Ampai Tanganuchitcharnchai; Clare L Ling; Saw Oo Tan; Elizabeth A Ashley; Mupawjay Pimanpanarak; Stuart D Blacksell; Nicholas P Day; Pratap Singhasivanon; Nicholas J White; François Nosten; Daniel H Paris
Journal: PLoS Negl Trop Dis Date: 2014-11-20